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Literature has concluded that a 2-day course of oral dexamethasone has comparable outcomes to a 5-day course of prednisone in the ED and hospital setting. A retrospective chart review was performed on children requiring in-house treatment with a corticosteroid (dexamethasone n = 23, prednisone n = 40) for acute asthma exacerbations at an ambulatory medical home. The rates of hospital admissions, ED visits, and symptom follow-up were similar between the 2 groups ( P &gt; .05). The cost for a course of dexamethasone was US$1.28 versus US$16.20 for prednisolone. The average cost for an asthma exacerbation office visit was US$79.89 compared with US$3113.28 for an ED visit. A 2-day course of oral dexamethasone appears to be a promising clinical and cost-effective treatment for acute asthma exacerbations at the primary care level.<\/jats:p>","DOI":"10.1177\/0009922818809466","type":"journal-article","created":{"date-parts":[[2018,10,31]],"date-time":"2018-10-31T08:24:10Z","timestamp":1540974250000},"page":"151-158","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Oral Dexamethasone to Control Wheezing in Children at an Outpatient Clinic"],"prefix":"10.1177","volume":"58","author":[{"given":"Angela S.","family":"Volk","sequence":"first","affiliation":[{"name":"Texas Children\u2019s Hospital, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie A.","family":"Marton","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brittany S.","family":"Richardson","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Rauda","sequence":"additional","affiliation":[{"name":"Texas Children\u2019s Health Plan, Bellaire, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heidi L.","family":"Schwarzwald","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2524-6256","authenticated-orcid":false,"given":"Neel M.","family":"Naik","sequence":"additional","affiliation":[{"name":"Baylor College of Medicine, Houston, TX, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,10,31]]},"reference":[{"key":"bibr1-0009922818809466","unstructured":"Centers for Disease Control and Prevention. 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