{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T14:53:21Z","timestamp":1787496801456,"version":"build-2736575974"},"reference-count":29,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2019,3,19]],"date-time":"2019-03-19T00:00:00Z","timestamp":1552953600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:p>Aim. To characterize antibiotic (ab) prescriptions in children. Methods. Evaluation of outpatient ab prescriptions in a 3-year cohort of children in primary care using a data warehouse (Massachusetts Health Disparities Repository) by comorbid conditions, demographics, and clinical indication. Results. A total of 15 208 children with nearly 120 000 outpatient visits were included. About one third had a comorbid condition (most commonly asthma). Among the 30 000 ab prescriptions, first-line penicillins and macrolides represented the most frequent ab (70%), followed by cephalosporins (16%). Comorbid children had 54.3 ab prescriptions\/100 child-years versus 38.8 in children without comorbidity; ab prescription was higher in urinary tract infections (&gt;60% of episodes), otitis, lower respiratory tract infections (&gt;50%), especially in comorbid children and children under 2 year old. Ab prescriptions were significantly associated with younger age, emergency room visit, comorbid children, and acute infections. Discussion. A clinical data warehouse could help in designing appropriate antimicrobial stewardship programs and represent a potential assessment tool.<\/jats:p>","DOI":"10.1177\/0009922819834278","type":"journal-article","created":{"date-parts":[[2019,3,19]],"date-time":"2019-03-19T03:26:27Z","timestamp":1552965987000},"page":"681-690","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Antibiotic Prescribing in Outpatient Children: A Cohort From a Clinical Data Warehouse"],"prefix":"10.1177","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7934-8912","authenticated-orcid":false,"given":"Leslie","family":"Grammatico-Guillon","sequence":"first","affiliation":[{"name":"Boston University, Boston, MA, USA"},{"name":"Teaching Hospital of Tours, University of Tours, Tours, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly","family":"Shea","sequence":"additional","affiliation":[{"name":"Boston University, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1099-9175","authenticated-orcid":false,"given":"S. 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