{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:23:51Z","timestamp":1777526631056,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2019,7,17]],"date-time":"2019-07-17T00:00:00Z","timestamp":1563321600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:p>We reviewed medical records of children with orbital cellulitis with positive cultures at a tertiary institution from 2005 to 2018 to identify microbiology trends and features associated with methicillin-resistant Staphylococcus aureus (MRSA) cases. Cultures obtained from the orbits (n = 33), sinuses (n = 31), and dural cavities (n = 4) had yields of 66.7%, 61.3%, and 75%, respectively, compared with 17.6% of blood cultures (n = 69). Fifty-five patients had positive culture results. Staphylococcus aureus was the most common pathogen isolated (n = 19), followed by Streptococcus species, most commonly Streptococcus anginosus (n = 8). The most frequently prescribed antibiotic combination regimen was ampicillin-sulbactam followed by amoxicillin-clavulanate. There were 8 cases of MRSA. MRSA was associated with an age of presentation &lt;1 year old ( P = .034). Other clinical features were similar between MRSA and non-MRSA cases. In infants and neonates, or those with epidemiologic risk factors, MRSA should also be considered.<\/jats:p>","DOI":"10.1177\/0009922819864587","type":"journal-article","created":{"date-parts":[[2019,7,17]],"date-time":"2019-07-17T03:27:29Z","timestamp":1563334049000},"page":"1056-1062","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":20,"title":["Microbiology of Pediatric Orbital Cellulitis and Trends in Methicillin-Resistant\n                    <i>Staphylococcus aureus<\/i>\n                    Cases"],"prefix":"10.1177","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0365-7214","authenticated-orcid":false,"given":"Jerry","family":"Hsu","sequence":"first","affiliation":[{"name":"Northwestern University, Chicago, IL, USA"},{"name":"Ann & Robert H. Lurie Children\u2019s Hospital of Chicago, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison D.","family":"Treister","sequence":"additional","affiliation":[{"name":"Northwestern University, Chicago, IL, USA"},{"name":"Ann & Robert H. Lurie Children\u2019s Hospital of Chicago, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hantamalala","family":"Ralay Ranaivo","sequence":"additional","affiliation":[{"name":"Ann & Robert H. Lurie Children\u2019s Hospital of Chicago, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne H.","family":"Rowley","sequence":"additional","affiliation":[{"name":"Northwestern University, Chicago, IL, USA"},{"name":"Ann & Robert H. 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