{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:54:59Z","timestamp":1792799699463,"version":"4.5.0"},"reference-count":36,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2022,7,26]],"date-time":"2022-07-26T00:00:00Z","timestamp":1658793600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Division of Adolescent and Transition Medicine and Division of Orthopedic Surgery, Cincinnati Children\u2019s Hospital Medical Center","id":[{"id":"https:\/\/ror.org\/01hcyya48","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Center for Clinical and Translational Science Training at the University of Cincinnati funded by the National Institutes of Health (NIH) Clinical and Translational Science Award","id":[{"id":"https:\/\/ror.org\/03fefqk78","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:p>Adolescents with overweight\/obesity are at risk for vitamin D insufficiency and deficiency. Both overweight\/obesity and vitamin D insufficiency\/deficiency may predispose to fractures. We enrolled 103 participants (53.3% females, 15.9 \u00b1 2.2 years) in a retrospective case-control study to determine whether an association exists between fractures and a low 25-hydroxyvitamin D (25[OH]D) among adolescents whose body mass index (BMI) \u2265 85 percentile. Cases (n = 28) sustaining a low\/medium impact fracture were matched to controls (n = 75) without a fracture history. A conditional-logistic regression analysis addressing the common vitamin D insufficiency\/deficiency cutoffs was used. Overweight, obesity, and significant obesity rates were 10.7%, 53.4%, and 35.9%, respectively. Mean (\u00b1SD) 25(OH)D was 16.5 \u00b1 6.4 ng\/mL. In all, 25(OH)D insufficiency rates (level &lt;20 ng\/mL) were 70.5%. Matched cases and controls had similar 25(OH)D insufficiency\/deficiency rates ( P &gt; .05). Controlling for race and seasonality showed no association between fractures and 25(OH)D insufficiency\/deficiency ( P &gt; .05). These data suggest that fractures are not associated with low 25(OH)D levels among adolescents whose BMI \u2265 85th percentile.<\/jats:p>","DOI":"10.1177\/00099228221112461","type":"journal-article","created":{"date-parts":[[2022,7,27]],"date-time":"2022-07-27T00:34:44Z","timestamp":1658882084000},"page":"107-114","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Relationship Between Hypovitaminosis D and Fractures Among Adolescents With Overweight or Obesity"],"prefix":"10.1177","volume":"62","author":[{"given":"David","family":"Segal","sequence":"first","affiliation":[{"name":"Division of Orthopaedic Surgery, Cincinnati Children\u2019s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA"},{"name":"Division of Orthopaedic Surgery, Meir Medical Center and Tel Aviv University, Kfar Saba, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6016-2453","authenticated-orcid":false,"given":"Adi","family":"Ziv","sequence":"additional","affiliation":[{"name":"Division of Adolescent and Transition Medicine, Cincinnati Children\u2019s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA"},{"name":"Adolescent Medicine Unit, Department of Day Care Hospitalization, Schneider Children\u2019s Medical Center of Israel and Sackler Faculty of Medicine, Tel Aviv University, Petach Tikva, Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Meisman","sequence":"additional","affiliation":[{"name":"Division of Adolescent and Transition Medicine, Cincinnati Children\u2019s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan","family":"Fry","sequence":"additional","affiliation":[{"name":"Division of Adolescent and Transition Medicine, Cincinnati Children\u2019s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mekibib","family":"Altaye","sequence":"additional","affiliation":[{"name":"Division of Biostatistics and Epidemiology, Cincinnati Children\u2019s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine M.","family":"Gordon","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Texas Children\u2019s Hospital and Baylor College of Medicine, Houston, TX, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,7,26]]},"reference":[{"key":"bibr1-00099228221112461","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2329C"},{"key":"bibr2-00099228221112461","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.6361"},{"key":"bibr3-00099228221112461","doi-asserted-by":"publisher","DOI":"10.1007\/s11914-014-0226-z"},{"key":"bibr4-00099228221112461","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-012-2621-z"},{"key":"bibr5-00099228221112461","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-015-3440-3"},{"key":"bibr6-00099228221112461","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.1999.14.10.1672"},{"key":"bibr7-00099228221112461","doi-asserted-by":"publisher","DOI":"10.1001\/jama.290.11.1479"},{"key":"bibr8-00099228221112461","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-012-9615-4"},{"key":"bibr9-00099228221112461","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2015.04.020"},{"key":"bibr10-00099228221112461","doi-asserted-by":"publisher","DOI":"10.3390\/nu5093551"},{"key":"bibr11-00099228221112461","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(17)30306-5"},{"key":"bibr12-00099228221112461","doi-asserted-by":"publisher","DOI":"10.1007\/s00787-017-0949-3"},{"key":"bibr13-00099228221112461","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadohealth.2019.08.025"},{"key":"bibr14-00099228221112461","first-page":"1","volume":"12","author":"Magge SN","year":"2018","journal-title":"J Clin Transl Endocrinol"},{"key":"bibr15-00099228221112461","unstructured":"DiaSorin SpA. 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