{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T13:13:16Z","timestamp":1780578796622,"version":"3.54.1"},"reference-count":30,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2022,10,10]],"date-time":"2022-10-10T00:00:00Z","timestamp":1665360000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:p>We reviewed patients with chromosome 22q11.2 deletion syndrome. We analyzed cardiovascular findings in patients with confirmed chromosome 22q11.2 deletion syndrome live-born in Nevada between March 2007 and September 2020. We identified 60 patients. Of the 60 patients, 32 (53%) were female. Of the 60, 48 (80%) had a conotruncal abnormality (including isolated vascular rings): 23 of 32 (72%) for females versus 25 of 28 (89%) for males, P = .41. However, 11 (34%) of 32 females had a right aortic arch; whereas, 21 (75%) of 28 males had a right aortic arch, P = .007. In conclusion, in our patient cohort, we found conotruncal malformations were common. However, we noted males were statistically more likely to have a right aortic arch than females. To the best of our knowledge, this male-female aortic arch laterality difference in patients with chromosome 22q11.2 deletion syndrome has not been previously noted.<\/jats:p>","DOI":"10.1177\/00099228221127730","type":"journal-article","created":{"date-parts":[[2022,10,10]],"date-time":"2022-10-10T09:28:07Z","timestamp":1665394087000},"page":"345-348","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Aortic Arch Laterality in Chromosome 22q11.2 Deletion Syndrome: Male-Female Difference"],"prefix":"10.1177","volume":"62","author":[{"given":"William N.","family":"Evans","sequence":"first","affiliation":[{"name":"Children\u2019s Heart Center Nevada, Las Vegas, NV, USA"},{"name":"Division of Pediatric Cardiology, Department of Pediatrics, Kirk Kerkorian School of Medicine, University of Nevada, Las Vegas, Las Vegas, NV, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruben J.","family":"Acherman","sequence":"additional","affiliation":[{"name":"Children\u2019s Heart Center Nevada, Las Vegas, NV, USA"},{"name":"Division of Pediatric Cardiology, Department of Pediatrics, Kirk Kerkorian School of Medicine, University of Nevada, Las Vegas, Las Vegas, NV, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1198-5787","authenticated-orcid":false,"given":"Humberto","family":"Restrepo","sequence":"additional","affiliation":[{"name":"Children\u2019s Heart Center Nevada, Las Vegas, NV, USA"},{"name":"Division of Pediatric Cardiology, Department of Pediatrics, Kirk Kerkorian School of Medicine, University of Nevada, Las Vegas, Las Vegas, NV, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,10,10]]},"reference":[{"key":"bibr1-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1007\/BF00278938"},{"issue":"5","key":"bibr2-00099228221127730","first-page":"924","volume":"50","author":"Driscoll DA","year":"1992","journal-title":"Am J Hum Genet"},{"key":"bibr3-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320440237"},{"key":"bibr4-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1542\/peds.112.1.101"},{"key":"bibr5-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1597\/05-070.1"},{"key":"bibr6-00099228221127730","doi-asserted-by":"publisher","DOI":"10.11005\/jbm.2013.20.1.57"},{"key":"bibr7-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1002\/ddrr.10"},{"issue":"11","key":"bibr8-00099228221127730","first-page":"642","volume":"163","author":"Rauch R","year":"2004","journal-title":"Eur J Pediatr"},{"key":"bibr9-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2010.01.333"},{"key":"bibr10-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2011.02271.x"},{"key":"bibr11-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1002\/uog.15766"},{"key":"bibr12-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1002\/pd.5015"},{"key":"bibr13-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1002\/pd.5020"},{"key":"bibr14-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1002\/pd.5029"},{"key":"bibr15-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1038\/35065105"},{"key":"bibr16-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.10358"},{"key":"bibr17-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1242\/dev.028902"},{"key":"bibr18-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-009-9613-0"},{"key":"bibr19-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-013-0384-6"},{"key":"bibr20-00099228221127730","doi-asserted-by":"publisher","DOI":"10.2147\/TACG.S82105"},{"key":"bibr21-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2008.03.023"},{"key":"bibr22-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1016\/j.sempedsurg.2021.151128"},{"key":"bibr23-00099228221127730","unstructured":"National vital statistics reports. Accessed 1 October 2021. http:\/\/www.cdc.gov\/nchs\/products\/nvsr.htm."},{"key":"bibr24-00099228221127730","doi-asserted-by":"publisher","DOI":"10.15557\/JoU.2019.0004"},{"key":"bibr25-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951113000644"},{"key":"bibr26-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-013-0694-4"},{"key":"bibr27-00099228221127730","unstructured":"Abbott ME. Atlas of Congenital Heart Disease. New York, NY: American Heart Association; 1936:60-61."},{"key":"bibr28-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.35.2.189"},{"key":"bibr29-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-002-9401-6"},{"key":"bibr30-00099228221127730","doi-asserted-by":"publisher","DOI":"10.1007\/BF00431315"}],"container-title":["Clinical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00099228221127730","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00099228221127730","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00099228221127730","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:32:16Z","timestamp":1777393936000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1177\/00099228221127730"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,10]]},"references-count":30,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["10.1177\/00099228221127730"],"URL":"https:\/\/doi.org\/10.1177\/00099228221127730","relation":{},"ISSN":["0009-9228","1938-2707"],"issn-type":[{"value":"0009-9228","type":"print"},{"value":"1938-2707","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,10]]}}}