{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:36:24Z","timestamp":1777527384235,"version":"3.51.4"},"reference-count":33,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T00:00:00Z","timestamp":1693440000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2024,6]]},"abstract":"<jats:p>Down syndrome (DS) is characterized by varying degrees of mental retardation and delay in neurocognitive functions. Herein, we analyzed the morphometric shape of the corpus callosum (CC) in children with DS. Twenty-three DS cases underwent magnetic resonance imaging and have grossly normal CC, and 23 control group cases were included in this retrospective study (2012-2020). The CC was obtained from T2-weighted mid-sagittal images, and certain anatomical points were marked on the CC. Statistical geometric shapes and deformations of CC were evaluated for both groups. The age range of patients with DS and control group was 6 to 42 months. A statistically significant difference was found in the shape of CC between the groups ( P &lt; .001). Deformation was most evident in the splenium in the DS group.<\/jats:p>","DOI":"10.1177\/00099228231196933","type":"journal-article","created":{"date-parts":[[2023,8,31]],"date-time":"2023-08-31T07:50:49Z","timestamp":1693468249000},"page":"815-821","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Morphometric Shape Analysis of Corpus Callosum in Children With Down Syndrome"],"prefix":"10.1177","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0047-1780","authenticated-orcid":false,"given":"Ba\u015fak","family":"Erdemli G\u00fcrsel","sequence":"first","affiliation":[{"name":"Department of Radiology, Bursa Uluda\u011f University Faculty of Medicine, Bursa, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2382-290X","authenticated-orcid":false,"given":"\u0130lker","family":"Ercan","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Bursa Uluda\u011f University Faculty of Medicine, Bursa, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130brahim","family":"\u015eahin","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Bursa Uluda\u011f University Institute of Health Sciences, Bursa, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00f6khan","family":"\u00d6ngen","sequence":"additional","affiliation":[{"name":"Department of Radiology, Bursa Uluda\u011f University Faculty of Medicine, Bursa, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,8,31]]},"reference":[{"issue":"1","key":"bibr1-00099228231196933","first-page":"27","volume":"4","author":"Ercan \u0130","year":"2012","journal-title":"Turkiye Klinikleri J Biostat"},{"key":"bibr2-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.anthro.34.081804.120613"},{"key":"bibr3-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1706537"},{"key":"bibr4-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0039804"},{"key":"bibr5-00099228231196933","volume-title":"Gray\u2019s Anatomy: The Anatomical Basis of Clinical Practice","author":"Standring S.","year":"2008"},{"key":"bibr6-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.160.10.1870"},{"key":"bibr7-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-016-4626-6"},{"key":"bibr8-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2003.10.022"},{"key":"bibr9-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpsy.2008.02.002"},{"key":"bibr10-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1177\/002221949102400302"},{"key":"bibr11-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2019.02.180"},{"key":"bibr12-00099228231196933","volume-title":"Normal Development of the Neonatal and Infant Brain","author":"Barkovich A.","year":"1990"},{"key":"bibr13-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-198511000-00004"},{"key":"bibr14-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1002\/ar.22493"},{"issue":"8","key":"bibr15-00099228231196933","first-page":"51","volume":"9","author":"Ercan I","year":"2008","journal-title":"Int J Tom Stat"},{"key":"bibr16-00099228231196933","first-page":"99","volume-title":"Assessment for Counselors","volume":"2006","author":"Dimitrov DM"},{"key":"bibr17-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617718000206"},{"key":"bibr18-00099228231196933","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.151.1.171"},{"key":"bibr19-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901320103"},{"key":"bibr20-00099228231196933","volume":"10","author":"LaMantia P","year":"1984","journal-title":"Soc Neurosci Abstr"},{"key":"bibr21-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2003.01614.x"},{"key":"bibr22-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1203\/01.pdr.0000190580.88391.9a"},{"key":"bibr23-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1990.00530050049011"},{"key":"bibr24-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.56.7.972"},{"key":"bibr25-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.10068"},{"key":"bibr26-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1016\/s0028-3843(14)60107-9"},{"issue":"1","key":"bibr27-00099228231196933","first-page":"19","volume":"28","author":"Carducci F","year":"2013","journal-title":"Funct Neurol"},{"key":"bibr28-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1007\/s00234-010-0696-3"},{"key":"bibr29-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1111\/desc.12360"},{"key":"bibr30-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/251308"},{"key":"bibr31-00099228231196933","doi-asserted-by":"publisher","DOI":"10.3171\/JNS\/2008\/108\/3\/0608"},{"key":"bibr32-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(16)00063-6"},{"key":"bibr33-00099228231196933","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1989.00520440031017"}],"container-title":["Clinical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00099228231196933","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00099228231196933","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00099228231196933","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:33:01Z","timestamp":1777393981000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00099228231196933"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,31]]},"references-count":33,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["10.1177\/00099228231196933"],"URL":"https:\/\/doi.org\/10.1177\/00099228231196933","relation":{},"ISSN":["0009-9228","1938-2707"],"issn-type":[{"value":"0009-9228","type":"print"},{"value":"1938-2707","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,31]]}}}