{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:36:20Z","timestamp":1777527380682,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T00:00:00Z","timestamp":1695686400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:p>\n                    The objective of this study is to describe causative pathogens and current antibiotic management among hospitalized children with orbital cellulitis. This retrospective study, performed at a tertiary care children\u2019s health system, included patients up to 18 years old who presented with radiographic evidence of orbital cellulitis from 2012 to 2019. Of the 298 patients included in the study, 103 had surgery and an intraoperative culture obtained. A pathogen was recovered in 86 cultures (83.5%). The most common pathogens were\n                    <jats:italic toggle=\"yes\">Streptococcus anginosus<\/jats:italic>\n                    group (26.2%),\n                    <jats:italic toggle=\"yes\">Streptococcus pyogenes<\/jats:italic>\n                    (11.7%), methicillin-susceptible\n                    <jats:italic toggle=\"yes\">Staphylococcus aureus<\/jats:italic>\n                    (10.7%), and\n                    <jats:italic toggle=\"yes\">Streptococcus pneumoniae<\/jats:italic>\n                    (9.7%). Only 8\/194 (4.1%) blood cultures returned positive. Median duration of intravenous antibiotics was 4 days and median total duration was 17 days. The most common empiric regimen prescribed was ceftriaxone and clindamycin (64.1%). Despite low incidence of methicillin-resistant\n                    <jats:italic toggle=\"yes\">S aureus<\/jats:italic>\n                    , empiric antibiotics often consisted of 2 antibiotics to ensure coverage for this bacterium.\n                  <\/jats:p>","DOI":"10.1177\/00099228231202158","type":"journal-article","created":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T02:44:40Z","timestamp":1695782680000},"page":"214-221","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Bugs Behind the Bulging Eyeball: Microbiology and Antibiotic Management in Orbital Cellulitis With or Without Subperiosteal Abscess"],"prefix":"10.1177","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4550-1522","authenticated-orcid":false,"given":"Gargi","family":"Mukherjee","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Emory University\/Children\u2019s Healthcare of Atlanta, Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristine","family":"Sufcak","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Emory University\/Children\u2019s Healthcare of Atlanta, Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicole","family":"Hames","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Emory University\/Children\u2019s Healthcare of Atlanta, Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Lantis","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Emory University\/Children\u2019s Healthcare of Atlanta, Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,9,26]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1542\/pir.31-6-242."},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2019.02.003."},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1542\/hpeds.2017-0040."},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-198605000-00018."},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197009000-00007."},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/626809."},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2018.05.006."},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/J.IJPORL.2020.110078."},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2013.1703."},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(00)00178-0."},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2010-2117."},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/JPIDS\/PIAC006."},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/0009922819864587."},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/J.IJPORL.2019.109695."},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2007.04.049."},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1080\/01676830.2020.1862247."},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2431-14-199."},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.12788\/JHM.3707."}],"container-title":["Clinical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00099228231202158","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00099228231202158","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00099228231202158","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:33:00Z","timestamp":1777393980000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00099228231202158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,26]]},"references-count":18,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1177\/00099228231202158"],"URL":"https:\/\/doi.org\/10.1177\/00099228231202158","relation":{},"ISSN":["0009-9228","1938-2707"],"issn-type":[{"value":"0009-9228","type":"print"},{"value":"1938-2707","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,26]]}}}