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This study aimed to evaluate renal and extrarenal complications in children with horseshoe kidney and crossed fused renal ectopia (CFRE) and to determine their clinical significance. Tc-99m dimercaptosuccinic acid (Tc-99m DMSA) scintigraphies of 759 pediatric patients were retrospectively reviewed, identifying 40 cases (5.27%) of renal fusion anomalies: 34 with horseshoe kidney, 5 with CFRE, and 1 with triple kidney. While 45% were asymptomatic, abdominal pain was the most common symptom. Vesicoureteral reflux and ureteropelvic junction stenosis were each found in 5%, and nephrolithiasis in 7.5%. Surgery was required in 7.5% of patients, with no cases of chronic renal failure. Understanding the etiopathogenesis and imaging features of these anomalies is crucial for effective clinical management.<\/jats:p>","DOI":"10.1177\/00099228261416161","type":"journal-article","created":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T04:20:22Z","timestamp":1769833222000},"page":"682-688","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Significance and Prognosis of Renal Fusion Anomalies Detected by Tc-99m Dimercaptosuccinic Acid Scintigraphy"],"prefix":"10.1177","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2553-5514","authenticated-orcid":false,"given":"Buket","family":"Esen Agar","sequence":"first","affiliation":[{"name":"Department of Pediatric Nephrology, Faculty of Medicine, Firat University, Elazig, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0645-8170","authenticated-orcid":false,"given":"Metin Kaya","family":"Gurgoze","sequence":"additional","affiliation":[{"name":"Department of Pediatric Nephrology and Rheumatology, Faculty of Medicine, Firat University, Elazig, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4410-0444","authenticated-orcid":false,"given":"Aslihan","family":"Kara","sequence":"additional","affiliation":[{"name":"Department of Pediatric Nephrology, Faculty of Medicine, Firat University, Elazig, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,1,30]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"85","volume-title":"Pediatric Nephrology","author":"Goodyer P","unstructured":"Goodyer P, Gupta IR, Westland R, et al. 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