{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T12:07:10Z","timestamp":1779019630015,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T00:00:00Z","timestamp":1770163200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To describe the clinical presentation at diagnosis and identify risk factors affecting outcomes in patients with juvenile spondyloarthropathy (JSpA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This retrospective cohort study reviewed records of patients \u226418 years old diagnosed with JSpA (2008-2023) at a pediatric rheumatology clinic, with at least 2 follow-up visits. Remission was defined as (1) on medication (inactive disease \u22656 months) or (2) off medication (inactive disease \u226512 months).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Eighty-eight patients were included; 90.9% were male. The mean age of onset was 12.6 years. Peripheral arthritis (77.3%) and enthesitis (39.8%) were common. Sacroiliitis was found in 56.8% at diagnosis. Risk factors associated with sacroiliitis included peripheral arthritis and enthesitis, polyarticular, and hip involvement. Golimumab and etanercept were anti-tumor necrosis factor (TNF) agents frequently used. Clinical remission on and off medication occurred in 33% and 10.2%, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The JSpA in this cohort demonstrated substantial disease burden, with frequent axial and peripheral involvement. Although 43.2% of patients achieved clinical remission, sustained remission off medication was observed in only 10.2%, reflecting the chronic disease course. Early diagnosis and optimized treatment strategies remain essential to improve outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00099228261416166","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T05:31:26Z","timestamp":1770269486000},"page":"660-674","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Features and Outcome of Patients With Juvenile Spondyloarthropathy in a Tertiary Hospital in the Philippines"],"prefix":"10.1177","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-0198-7423","authenticated-orcid":false,"given":"Maria Catherine Joyce D.","family":"Garcia","sequence":"first","affiliation":[{"name":"Section of Pediatric Rheumatology, Department of Pediatrics, University of Santo Tomas Hospital, Manila, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0214-0827","authenticated-orcid":false,"given":"Christine B.","family":"Bernal","sequence":"additional","affiliation":[{"name":"Section of Pediatric Rheumatology, Department of Pediatrics, University of Santo Tomas Hospital, Manila, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8649-7908","authenticated-orcid":false,"given":"Ma. Theresa M.","family":"Collante","sequence":"additional","affiliation":[{"name":"Section of Pediatric Rheumatology, Department of Pediatrics, University of Santo Tomas Hospital, Manila, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,2,4]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12969-018-0238-9"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.5152\/eurjrheum.2021.20235"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-016-0603-y"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcl.2018.03.006"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2022.1074239"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kew446"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2021-001728"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20497"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2016-000366"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.680916"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/s42358-024-00378-8"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.rdc.2021.07.001"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2020-001450"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-023-05602-z"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.666772"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1080\/14656566.2020.1796970"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-017-1297-x"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40272-020-00416-0"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11926-021-01036-4"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/acr2.11353"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-022-02877-9"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.681621"},{"issue":"12","key":"e_1_3_2_24_2","first-page":"2140","article-title":"Genuine ankylosing spondylitis in children: a case-control study of patients with early definite disease according to adult onset criteria","volume":"23","author":"Burgos-Vargas R","year":"1996","unstructured":"Burgos-Vargas R, V\u00e1zquez-Mellado J, Cassis N, et al. 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