{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T08:00:13Z","timestamp":1780732813086,"version":"3.54.1"},"reference-count":65,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Shannxi Provincial key research and development program","award":["No. S2023-YF-YBSF-1362"],"award-info":[{"award-number":["No. S2023-YF-YBSF-1362"]}]},{"name":"Shannxi Provincial key research and development program","award":["No. 2024SF2-GjHX-20"],"award-info":[{"award-number":["No. 2024SF2-GjHX-20"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:p>\n                    We aimed to identify modifiable risk factors affecting ambulation in Chinese children with Duchenne muscular dystrophy (DMD) by analyzing follow-up data from 161 patients with DMD. Continuous variables were compared using\n                    <jats:italic toggle=\"yes\">t<\/jats:italic>\n                    -test or the Wilcoxon rank-sum test (for non-normally distributed variables). Cox regression determined factors influencing walking ability, and the log-rank test compared retention of walking ability between school-going and non-school-going patients. Hormone therapy (HR 3.72;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .033), school attendance (HR 5.20;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .010), and Disability and Social Support Rating Scale scores (HR 1.16;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .021) significantly predicted loss of ambulation. Vitamin D levels were lower in ambulatory children with DMD who lost the ability to walk (F = 26.246,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .000). Hormone therapy improved the 10-m walking time, while rehabilitation influenced the decumbent position and walking times. Early hormone therapy combined with consistent rehabilitation and school engagement is recommended for preserving ambulation.\n                  <\/jats:p>","DOI":"10.1177\/00099228261429136","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T07:07:51Z","timestamp":1774249671000},"page":"912-927","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Investigation of Walking Ability in 161 Patients With Duchenne Muscular Dystrophy"],"prefix":"10.1177","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7843-3885","authenticated-orcid":false,"given":"Ying","family":"Guo","sequence":"first","affiliation":[{"name":"Neurology Department, Northwest Women\u2019s and Children\u2019s Hospital, Xi\u2019an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6428-7691","authenticated-orcid":false,"given":"Xiaofang","family":"Wu","sequence":"additional","affiliation":[{"name":"Neurology Department, Northwest Women\u2019s and Children\u2019s Hospital, Xi\u2019an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4734-4428","authenticated-orcid":false,"given":"Yun","family":"Xie","sequence":"additional","affiliation":[{"name":"Laboratory Department, Northwest Women\u2019s and Children\u2019s Hospital, Xi\u2019an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8960-1037","authenticated-orcid":false,"given":"Wen","family":"Zhai","sequence":"additional","affiliation":[{"name":"Reproductive Center, Northwest Women\u2019s and Children\u2019s Hospital, Xi\u2019an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-0949-1735","authenticated-orcid":false,"given":"Na","family":"Cai","sequence":"additional","affiliation":[{"name":"Reproductive Center, Northwest Women\u2019s and Children\u2019s Hospital, Xi\u2019an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9736-9776","authenticated-orcid":false,"given":"Wenhao","family":"Shi","sequence":"additional","affiliation":[{"name":"Reproductive Center, Northwest Women\u2019s and Children\u2019s Hospital, Xi\u2019an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1519-7516","authenticated-orcid":false,"given":"Hua","family":"Chen","sequence":"additional","affiliation":[{"name":"Neurology Department, Northwest Women\u2019s and Children\u2019s Hospital, Xi\u2019an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1411-9502","authenticated-orcid":false,"given":"Tingting","family":"Liu","sequence":"additional","affiliation":[{"name":"Neurology Department, Northwest Women\u2019s and Children\u2019s Hospital, Xi\u2019an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-7658-2226","authenticated-orcid":false,"given":"Qiaowei","family":"Shi","sequence":"additional","affiliation":[{"name":"Neurology Department, Northwest Women\u2019s and Children\u2019s Hospital, Xi\u2019an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-1869-3100","authenticated-orcid":false,"given":"Xiao Ge","family":"Zhang","sequence":"additional","affiliation":[{"name":"Neurology Department, Northwest Women\u2019s and Children\u2019s Hospital, Xi\u2019an, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,23]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1080\/00207454.2020.1740218"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/345315a0"},{"key":"e_1_3_3_4_2","unstructured":"Darras BT Urion DK Ghosh PS. 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