{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T17:04:54Z","timestamp":1786122294272,"version":"build-2736575974"},"reference-count":26,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T00:00:00Z","timestamp":1777248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:p>\n                    In this retrospective single-centred cohort study, we investigated pathogens associated with paediatric airway infections during the 2023 surge of respiratory illnesses in Japan. Data from electronic medical records of children who underwent BioFire\u00ae Respiratory Panel testing were analysed. Among 228 hospitalized children, 306 pathogens were identified in 188 patients (82.45%), predominantly rhinovirus\/enterovirus (RV\/EV; 36.93%), respiratory syncytial virus (RSV; 12.75%), adenovirus (12.42%), and parainfluenza virus type 3 (PIV3; 9.48%). RV\/EV positivity was linked to higher rates of laboured breathing (25.34% vs 7.47%,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; .0001) and wheezing (26.03% vs 10.34%,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .0003). RSV-positivity was associated with increased rhonchi (16.67% vs 3.40%,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .0009) and crackles (22.22% vs 7.52%,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .025). Patients with RSV and PIV3 had significantly lower transcutaneous oxygen saturation than those with other viruses. RV\/EV were the most prevalent pathogens, underscoring the need for vigilance regarding viruses causing respiratory distress and hypoxemia in children.\n                  <\/jats:p>","DOI":"10.1177\/00099228261441926","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T06:04:07Z","timestamp":1777356247000},"page":"1044-1053","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Analysis of Pathogens Detected Using Multiplex PCR in Children After the COVID-19 Pandemic"],"prefix":"10.1177","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-6155-1723","authenticated-orcid":false,"given":"Yuji","family":"Hirai","sequence":"first","affiliation":[{"name":"Pediatrics, Yokohama Minami Kyousai Hospital, Yokohama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6605-545X","authenticated-orcid":false,"given":"Saori","family":"Deki","sequence":"additional","affiliation":[{"name":"Pediatrics, Yokohama Minami Kyousai Hospital, Yokohama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2065-7026","authenticated-orcid":false,"given":"Takashi","family":"Nishizawa","sequence":"additional","affiliation":[{"name":"Pediatrics, Yokohama Minami Kyousai Hospital, Yokohama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-6694-6587","authenticated-orcid":false,"given":"Hiroki","family":"Sugiyama","sequence":"additional","affiliation":[{"name":"Pediatrics, Yokohama Minami Kyousai Hospital, Yokohama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,4,27]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000030604"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000002712"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2023.1200617"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.lana.2021.100015"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2023.1212658"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/irv.13278"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2023-062574"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2013.11.005"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/8734504"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12225"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2019.02737"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.3390\/v8010016"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00077-12"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.3.278"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.179.2.1080"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.3390\/medicina58081133"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.82.s1.03"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI137117"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1584742"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.113.6.1758"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jit579"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.3390\/v13020262"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2014.07.010"},{"key":"e_1_3_3_25_2","first-page":"119","article-title":"Clinical presentation of children infected with human parainfluenza virus type 3","volume":"35","author":"Matsumoto K","year":"2023","unstructured":"Matsumoto K, Kano Z, Morooka Y, Teduka J, Mizuno Y, Furuno K. Clinical presentation of children infected with human parainfluenza virus type 3. J Soc Pediatr Infect Dis. 2023;35:119-127.","journal-title":"J Soc Pediatr Infect Dis"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e3181d743c8"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02553-06"}],"container-title":["Clinical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00099228261441926","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00099228261441926","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00099228261441926","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T08:57:21Z","timestamp":1786093041000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00099228261441926"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,27]]},"references-count":26,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1177\/00099228261441926"],"URL":"https:\/\/doi.org\/10.1177\/00099228261441926","relation":{},"ISSN":["0009-9228","1938-2707"],"issn-type":[{"value":"0009-9228","type":"print"},{"value":"1938-2707","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,27]]}}}