{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T17:04:00Z","timestamp":1786122240627,"version":"build-2736575974"},"reference-count":22,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T00:00:00Z","timestamp":1778025600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:p>\n                    Febrile seizures (FS) are the most common convulsive disorder in childhood and are classified into simple and complex subtypes. Although blood tests are not routinely required, certain laboratory parameters may provide additional information for distinguishing these subtypes. We conducted a single-center retrospective study of 67 children, including 41 with simple FS and 26 with complex FS. Laboratory and clinical findings were compared between groups. Venous blood gas analysis revealed significant differences in pH (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .039) and pCO\n                    <jats:sub>2<\/jats:sub>\n                    (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = .042). The area under the receiver operating characteristic (ROC) curve was 0.825 for pH (threshold 7.432) and 0.817 for pCO\n                    <jats:sub>2<\/jats:sub>\n                    (threshold 37.0 mm\u2009Hg). Seizure duration showed strong correlations with base excess (r = \u22120.85), pH (r = \u22120.77), ammonia (r = 0.76), and pCO\n                    <jats:sub>2<\/jats:sub>\n                    (r = 0.74). These findings suggest that venous blood gas parameters are associated with seizure duration and may reflect seizure severity rather than independently distinguishing FS subtypes.\n                  <\/jats:p>","DOI":"10.1177\/00099228261447635","type":"journal-article","created":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T09:06:26Z","timestamp":1778058386000},"page":"1080-1085","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Laboratory Findings for Simple and Complex Febrile Seizures"],"prefix":"10.1177","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7477-8005","authenticated-orcid":false,"given":"Yoshifumi","family":"Miyagi","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Haibara General Hospital, Makinohara City, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasunori","family":"Horiguchi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, International University of Health and Welfare, Atami Hospital, Atami City, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuyuki","family":"Yano","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Haibara General Hospital, Makinohara City, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosuke","family":"Urabe","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Haibara General Hospital, Makinohara City, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Kitagawa","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Haibara General Hospital, Makinohara City, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Kato","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Haibara General Hospital, Makinohara City, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kentoku","family":"Kin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Haibara General Hospital, Makinohara City, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,6]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.7573\/dic.212536"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pediatrneurol.2024.03.024"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197611042951901"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/epi.12429"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.29.3.297"},{"issue":"22","key":"e_1_3_3_7_2","first-page":"3380","article-title":"Neutrophil-to-lymphocyte ratio and red blood cell distribution width is a practical predictor for differentiation of febrile seizure types","volume":"18","author":"Goksugur SB","year":"2014","unstructured":"Goksugur SB, Kabakus N, Bekdas M, Demircioglu F. Neutrophil-to-lymphocyte ratio and red blood cell distribution width is a practical predictor for differentiation of febrile seizure types. Eur Rev Med Pharmacol Sci. 2014;18(22):3380-3385.","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-33373-3"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/8472795"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1590\/1984-0462\/2024\/42\/2023016"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-45911-9"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.24398"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2016.06.001"},{"key":"e_1_3_3_14_2","first-page":"2825","article-title":"Scikit-learn: machine learning in python","volume":"12","author":"Pedregosa F","year":"2011","unstructured":"Pedregosa F, Varoquaux G, Gramfort A, et al. 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