{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T14:45:23Z","timestamp":1792334723769,"version":"4.4.0"},"reference-count":31,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T00:00:00Z","timestamp":1784505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:p>\n                    Upper gastrointestinal involvement beyond the duodenum in pediatric celiac disease (CD) remains undercharacterized. We conducted a single-center retrospective analysis of children who underwent esophagogastroduodenoscopy, comparing CD cases with non-CD controls. Biopsies were graded using the modified Marsh-Oberhuber and Sydney systems;\n                    <jats:italic toggle=\"yes\">Helicobacter pylori<\/jats:italic>\n                    was assessed by histology and rapid urease testing. Outcomes were esophagitis, gastritis subtypes,\n                    <jats:italic toggle=\"yes\">H pylori<\/jats:italic>\n                    infection, peptic ulcers, and, in CD, associations with Marsh stage. Among 996 procedures, 260 (26.1%) had CD. Gastritis was common in both groups, with chronic active gastritis most frequent. Chronic lymphocytic gastritis was more prevalent in CD (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; .05), while\n                    <jats:italic toggle=\"yes\">H pylori<\/jats:italic>\n                    infection was lower (39.6% vs 50.3%;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; .05). Peptic ulcers were more frequent in CD, predominantly in the duodenal bulb (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; .001). Esophagitis showed an inverse relationship with Marsh stage (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; .05). These findings delineate distinct upper gastrointestinal features in pediatric CD and may support a more comprehensive evaluation of the upper gastrointestinal tract during diagnostic endoscopy.\n                  <\/jats:p>","DOI":"10.1177\/00099228261467862","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T06:23:00Z","timestamp":1784614980000},"page":"1308-1315","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Upper Gastrointestinal Involvement in Celiac Disease: Histopathologic and Endoscopic Findings\u2014A Retrospective Cross-sectional Study"],"prefix":"10.1177","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9332-9803","authenticated-orcid":false,"given":"Ye\u015fim","family":"Tural","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Kosuyolu Istanbul Medipol Hospital, Istanbul, T\u00fcrkiye"},{"name":"Department of Pediatrics, Zeynep Kamil Women and Children Diseases Training and Research Hospital, University of Health Sciences, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9967-1669","authenticated-orcid":false,"given":"Erdal","family":"Sar\u0131","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Zeynep Kamil Women and Children Diseases Training and Research Hospital, University of Health Sciences, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4772-796X","authenticated-orcid":false,"given":"Egemen","family":"Tural","sequence":"additional","affiliation":[{"name":"Department of Family Medicine, Kagithane District Health Directorate, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5553-6123","authenticated-orcid":false,"given":"Nevzat Aykut","family":"Bayrak","sequence":"additional","affiliation":[{"name":"Department of Pediatric Gastroenterology, Hepatology and Nutrition, Medipol Ac\u0131badem Regional Hospital, Istanbul, T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,20]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3109\/07853890.2010.505931"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-012-0311-2"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-016-1034-y"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-199302000-00013"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13249"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/2050640616684698"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2009.07.011"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2011.04666.x"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2009.06.023"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/dote.12419"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v25.i16.1928"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2020.03.010"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199610000-00001"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-199910000-00019"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e31821a23d0"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/ctg.2017.41"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199902000-00003"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.49.4.519"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.15171\/mejdd.2016.12"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwt234"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/hel.12691"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1159\/000514276"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0241156"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.5152\/tjg.2022.21360"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v28.i12.1272"},{"issue":"3","key":"e_1_3_2_27_2","article-title":"Helicobacter pylori and non-malignant upper gastrointestinal diseases","volume":"4","author":"Petkevi\u010dius V","year":"2022","unstructured":"Petkevi\u010dius V, Kup\u010dinskas J. Helicobacter pylori and non-malignant upper gastrointestinal diseases. Microb Health Dis. 2022;4(3):e721.","journal-title":"Microb Health Dis"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.4274\/cjms.2021.2021-50"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.5152\/TurkArchPediatr.2024.23312"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-018-5174-5"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.crphar.2024.100198"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1177\/2050313X241242932"}],"container-title":["Clinical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00099228261467862","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00099228261467862","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00099228261467862","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T14:24:36Z","timestamp":1792333476000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00099228261467862"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,20]]},"references-count":31,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["10.1177\/00099228261467862"],"URL":"https:\/\/doi.org\/10.1177\/00099228261467862","relation":{},"ISSN":["0009-9228","1938-2707"],"issn-type":[{"value":"0009-9228","type":"print"},{"value":"1938-2707","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,20]]}}}