{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:43:15Z","timestamp":1777524195051,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[1980,11,1]],"date-time":"1980-11-01T00:00:00Z","timestamp":341884800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[1980,11]]},"abstract":"<jats:p>In order to study predictors of fever response in children with radiologic pulmonary infiltrates treated with antibiotics, 156 children with pneumonia were evaluated with slide test C-reactive protein (CRP), white blood cell count (WBC), erythrocyte sedimentation rate (ESR), blood cultures, acute and con valescent viral and mycoplasma titers, and then followed clinically. Both CRP (+) at a serum dilution of 1:50 and WBC \u2265 15,000 were better predictors of rapid resolution of fever while the patient was receiving antibiotics than were ESR \u2265 30 or temperature \u2265 40 C. WBC \u2265 15,000 was nearly as specific but more sensitive than CRP (+) 1:50 for resolution of fever in either 8, 12 or 24 hours. Positive blood or lung bacterial cultures, but not four-fold or greater viral or mycoplasma titer increases, were also associated with rapid resolution of fever. WBC \u2265 15,000 is useful in predicting rapid fever response in children with pneumonia treated with antibiotics.<\/jats:p>","DOI":"10.1177\/000992288001901108","type":"journal-article","created":{"date-parts":[[2008,7,28]],"date-time":"2008-07-28T18:00:38Z","timestamp":1217268038000},"page":"753-760","source":"Crossref","is-referenced-by-count":13,"title":["Predicting Fever Response of Children with Pneumonia Treated with Antibiotics"],"prefix":"10.1177","volume":"19","author":[{"given":"Paul L.","family":"McCarthy","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Yaie University School of Medicine, and Yale-New Haven Hospital, New Haven, Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucille","family":"Tomasso","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Yaie University School of Medicine, and Yale-New Haven Hospital, New Haven, Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"JR","given":"Thomas F.","family":"Dolan","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Yaie University School of Medicine, and Yale-New Haven Hospital, New Haven, Connecticut"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1980,11,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(75)80584-1"},{"key":"atypb2","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1542\/peds.62.5.716","volume":"62","author":"McCarthy PL","year":"1978","journal-title":"Pediatrics"},{"key":"atypb3","first-page":"393","volume":"122","author":"Shuttleworth DB","year":"1971","journal-title":"Am J Dis Child"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(78)80448-X"},{"key":"atypb5","volume-title":"Radiographic findings and etiologic diagnosis in ambulatory childhood pneumonia","author":"McCarthy PL","year":"1980"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197306212882501"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1542\/peds.59.5.663"},{"key":"atypb8","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1542\/peds.37.2.270","volume":"37","author":"Felix NS","year":"1966","journal-title":"Pediatrics"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1970.tb17704.x"},{"key":"atypb10","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1542\/peds.57.6.861","volume":"59","author":"McCarthy PL","year":"1976","journal-title":"Pediatrics"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1084\/jem.52.4.561"}],"container-title":["Clinical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000992288001901108","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000992288001901108","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:22:53Z","timestamp":1777393373000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000992288001901108"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,11]]},"references-count":11,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1980,11]]}},"alternative-id":["10.1177\/000992288001901108"],"URL":"https:\/\/doi.org\/10.1177\/000992288001901108","relation":{},"ISSN":["0009-9228","1938-2707"],"issn-type":[{"value":"0009-9228","type":"print"},{"value":"1938-2707","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,11]]}}}