{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:56:08Z","timestamp":1777524968118,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[1982,7,1]],"date-time":"1982-07-01T00:00:00Z","timestamp":394329600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[1982,7]]},"abstract":"<jats:p>The usual presenting features of vitamin A intoxication are pseuotumor cerebri, skeletal pain, desquamative dermatitis, and hepatic inflammation. Our patient was a nine-year-old female who had increasing cough, dyspnea, and abdominal dis tention for a short time prior to admission. She was said to have been treated with 10,000 units vitamin A per day for skin rashes. Radiographic studies revealed a very large right sided pleural effusion, ascites, demineralized bones, and retarded skeletal maturation. The diagnosis of hypervitaminosis A was made. More detailed medical history confirmed that the child had, in actuality, received up to 300,000 units\/day of vitamin A plus desiccated liver pills and carrot juice for the previous year. Clinical symptoms completely abated following acute medical treatment for ascites and cessation of vitamin A intake. Several months later, a sample of liver, obtained and preserved at the time of exploratory laparotomy, was homogenized and extracted with ethanol\/hexane. The retinyl palmitate level was significantly elevated and consistent with vitamin A poisoning.<\/jats:p>","DOI":"10.1177\/000992288202100710","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T17:50:16Z","timestamp":1196099416000},"page":"435-440","source":"Crossref","is-referenced-by-count":16,"title":["Pleural Effusion and Ascites"],"prefix":"10.1177","volume":"21","author":[{"given":"Henrietta Kotlus","family":"Rosenberg","sequence":"first","affiliation":[{"name":"Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart","family":"Berezin","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sydney","family":"Heyman","sequence":"additional","affiliation":[{"name":"Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camillus","family":"Witzleben","sequence":"additional","affiliation":[{"name":"Department of Pathology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John B.","family":"Watkins","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1982,7,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1542\/peds.48.4.655","volume":"48","author":"Joint Committee Statement, Committee on Drugs and Nutrition","year":"1971","journal-title":"Pediatrics"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1977.03280170043024"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197408292910903"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(79)80231-0"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1980.01640270043010"},{"key":"atypb6","first-page":"2528","volume":"38","author":"Sporn MB","year":"1979","journal-title":"Fed Proc"},{"key":"atypb7","first-page":"132","volume":"119","author":"Rubin E.","year":"1970","journal-title":"Dis Child"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/32.12.2500"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1172\/JCI105468"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)39309-3"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1172\/JCI106393"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(71)90212-9"}],"container-title":["Clinical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000992288202100710","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000992288202100710","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:24:47Z","timestamp":1777393487000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000992288202100710"}},"subtitle":["Unusual Presenting Features in a Pediatric Patient with Vitamin A Intoxication"],"short-title":[],"issued":{"date-parts":[[1982,7]]},"references-count":12,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1982,7]]}},"alternative-id":["10.1177\/000992288202100710"],"URL":"https:\/\/doi.org\/10.1177\/000992288202100710","relation":{},"ISSN":["0009-9228","1938-2707"],"issn-type":[{"value":"0009-9228","type":"print"},{"value":"1938-2707","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,7]]}}}