{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:02:04Z","timestamp":1777525324113,"version":"3.51.4"},"reference-count":17,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[1984,7,1]],"date-time":"1984-07-01T00:00:00Z","timestamp":457488000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[1984,7]]},"abstract":"<jats:p>Serum levels of C-reactive protein (CRP) were measured within 96 hours of birth in 55 neonates with respiratory distress syndrome (RDS), 19 neonates with no significant medical illness other than an unstable cardiovascular state, and 13 neonates with a variety of pulmonary and extra pulmonary problems either alone or in combination with RDS. The median serum CRP level in patients with RDS (2 \u03bcg\/ml) was neither elevated nor different from CRP levels in infants with unstable cardiovascular systems (median CRP level, 2 \u03bcg\/ml); however, neonates with other prob lems including pneumonia, aspiration, and extrapulmonary sepsis had significantly elevated serum CRP values (median 24 \u03bcg\/ml). CRP levels are not elevated in neonatal RDS. Measurement of this acute phase reactant provides a rapid and reliable means of helping to distinguish infants with uncomplicated RDS from those with other serious pulmonary and extrapulmonary disease.<\/jats:p>","DOI":"10.1177\/000992288402300703","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T17:50:16Z","timestamp":1196099416000},"page":"381-383","source":"Crossref","is-referenced-by-count":6,"title":["Serum Levels of C-reactive Protein in Neonatal Respiratory Distress Syndrome"],"prefix":"10.1177","volume":"23","author":[{"given":"Roland F.","family":"Dyck","sequence":"first","affiliation":[{"name":"Departments of Medicine and Pediatrics, University Hospital, Saskatoon, Saskatchewan, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Bingham","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Pediatrics, University Hospital, Saskatoon, Saskatchewan, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonard","family":"Tan","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Pediatrics, University Hospital, Saskatoon, Saskatchewan, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan L.","family":"Rogers","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Pediatrics, University Hospital, Saskatoon, Saskatchewan, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1984,7,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.52.4.561"},{"key":"atypb2","first-page":"653","volume":"1981","author":"Pepys MB","journal-title":"Lancet"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780230609"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.1982.tb02244.x"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.32.12.1253"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1136\/ard.39.1.50"},{"key":"atypb7","unstructured":"Avery ME, Fletcher BD, Williams RG Hyaline membrane disease. In: Avery ME, Fletcher BD, Williams RG , eds. The lung and its disorders in the newborn infant . Philadelphia: WB Saunders, 1981:222."},{"key":"atypb8","unstructured":"Avery ME, Fletcher BD, Williams RG Infections. In: Avery ME, Fletcher BD, Williams RG , eds. The lung and its disorders in the newborn infant . Philadelphia: WB Saunders, 1981:203."},{"key":"atypb9","unstructured":"Hilliard JK, Schreiner RL Neonatal bacterial sepsis. In: Schreiner RL , ed. Care of the newborn. New York: Raven Press, 1981:148."},{"key":"atypb10","first-page":"712","volume":"25","author":"Bingham WT","year":"1979","journal-title":"Can Fam Phys"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(66)90246-6"},{"key":"atypb12","first-page":"32","volume":"30","author":"Pepys MB","year":"1977","journal-title":"Clin Exp Immunol"},{"key":"atypb13","unstructured":"Hollander M., Wolf DA Non-parametric statistical methods. 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