{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:00:14Z","timestamp":1777525214018,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[1984,11,1]],"date-time":"1984-11-01T00:00:00Z","timestamp":468115200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[1984,11]]},"abstract":"<jats:p>We report a child with the presentation of Wilson's disease as acute fulminant hepatic failure and severe hemolysis. Our review of the literature suggests the following criteria for considering this diagnosis in the child with acute liver failure: discordance between mildly elevated serum transaminases and extremely elevated bilirubin levels; anemia associated with hemolysis (increased reticulocytes in the absence of bleeding); elevated hepatic copper; and other copper metabolic abnormalities (elevated serum copper, excessive 24-hour urine copper excretion, and reduced serum ceruloplasmin). Establishing the correct diagnosis enhances the possibility of detecting asymptomatic siblings or other family members in whom early inauguration preventative therapy should be successful.<\/jats:p>","DOI":"10.1177\/000992288402301106","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T17:50:16Z","timestamp":1196099416000},"page":"637-640","source":"Crossref","is-referenced-by-count":16,"title":["Fatal Fulminant Hepatitis with Hemolysis in Wilson's Disease"],"prefix":"10.1177","volume":"23","author":[{"given":"Jerome R.","family":"Kraut","sequence":"first","affiliation":[{"name":"Lutheran General Hospital, Division of Pediatrics, Park Ridge, Illinois, The Children's Memorial Hospital, Division of Infectious Diseases, and Northwestern University Medical School, Department of Pediatrics, Chicago, Illinais"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ram","family":"Yogev","sequence":"additional","affiliation":[{"name":"Lutheran General Hospital, Division of Pediatrics, Park Ridge, Illinois, The Children's Memorial Hospital, Division of Infectious Diseases, and Northwestern University Medical School, Department of Pediatrics, Chicago, Illinais"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1984,11,1]]},"reference":[{"key":"atypb1","unstructured":"Alagille D., Odievre M. Liver and biliary tract disease in children. New York: Wiley & Sons, 1979:228."},{"key":"atypb2","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/S0031-3955(16)33218-7","volume":"22","author":"Sass-Kortsak A.","year":"1975","journal-title":"Pediatr Clin N Am"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1136\/adc.55.4.252"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(16)33904-9"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(71)80458-4"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-86-3-301"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1977.02120210048011"},{"key":"atypb8","first-page":"440","volume":"133","author":"Doering EJ","year":"1979","journal-title":"Am J Dis Child"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6088.660"},{"key":"atypb10","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1542\/peds.62.1.47","volume":"62","author":"Werlin SL","year":"1978","journal-title":"Pediatrics"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197806152982406"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(78)90261-5"},{"key":"atypb13","unstructured":"Trey C. Fulminant hepatic failure surveillance study. In: Saunders SJ, Terblanche J, eds. International liver conference. London: Pitman Medical Publishing Co. 1973: 120-8."},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1136\/adc.37.193.253"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(78)90238-X"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/48.3.279"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197503000-00002"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1172\/JCI103027"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1177\/003591576505800820"},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-86-3-285"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(80)90687-3"}],"container-title":["Clinical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000992288402301106","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000992288402301106","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:25:31Z","timestamp":1777393531000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000992288402301106"}},"subtitle":["Criteria for Diagnosis"],"short-title":[],"issued":{"date-parts":[[1984,11]]},"references-count":21,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1984,11]]}},"alternative-id":["10.1177\/000992288402301106"],"URL":"https:\/\/doi.org\/10.1177\/000992288402301106","relation":{},"ISSN":["0009-9228","1938-2707"],"issn-type":[{"value":"0009-9228","type":"print"},{"value":"1938-2707","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,11]]}}}