{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:03:36Z","timestamp":1777525416699,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[1985,11,1]],"date-time":"1985-11-01T00:00:00Z","timestamp":499651200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[1985,11]]},"abstract":"<jats:p>Two children aged 7 months with eczema herpeticum received treatment consisting of intravenous acyclovir and human plasma with a high titer of herpes simplex virus antibodies. One recovered following two recurrences, but the other died rapidly, suffering both septicemia due to Pseudomonas aeruginosa and herpetic encephalitis. In both cases, the virus involved was a herpes simplex virus type 1 (HSV 1). The various isolates obtained before, during and after treatment remained equally sen sitive to acyclovir. These observations highlight three points: (1) the unpredictable and sometimes dramatic development of eczema herpeticum in the young child; (2) the urgency of early diagnosis and treatment; (3) the role of environment in viral contamination.<\/jats:p>","DOI":"10.1177\/000992288502401118","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T18:53:11Z","timestamp":1196103191000},"page":"660-663","source":"Crossref","is-referenced-by-count":14,"title":["Eczema Herpeticum of the Child"],"prefix":"10.1177","volume":"24","author":[{"given":"D.","family":"Ingrand","sequence":"first","affiliation":[{"name":"Laboratoire de Bacteriologie-Virologie, Groupe hospitalier Pitie-Salpetriere, Paris, Centre hospitalier de Pontoise, and Centre hospitalier Intercommunal de Cr\u00e8teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Briquet","sequence":"additional","affiliation":[{"name":"Laboratoire de Bacteriologie-Virologie, Groupe hospitalier Pitie-Salpetriere, Paris, Centre hospitalier de Pontoise, and Centre hospitalier Intercommunal de Cr\u00e8teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.M.","family":"Babinet","sequence":"additional","affiliation":[{"name":"Laboratoire de Bacteriologie-Virologie, Groupe hospitalier Pitie-Salpetriere, Paris, Centre hospitalier de Pontoise, and Centre hospitalier Intercommunal de Cr\u00e8teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ph.","family":"Reinert","sequence":"additional","affiliation":[{"name":"Laboratoire de Bacteriologie-Virologie, Groupe hospitalier Pitie-Salpetriere, Paris, Centre hospitalier de Pontoise, and Centre hospitalier Intercommunal de Cr\u00e8teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.M.","family":"Huraux","sequence":"additional","affiliation":[{"name":"Laboratoire de Bacteriologie-Virologie, Groupe hospitalier Pitie-Salpetriere, Paris, Centre hospitalier de Pontoise, and Centre hospitalier Intercommunal de Cr\u00e8teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1985,11,1]]},"reference":[{"key":"atypb1","first-page":"324","volume":"116","author":"Monif Grg","year":"1968","journal-title":"Am J Dis Child"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1966.01600200018002"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1979.04010030019007"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1982.01650200065019"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1983.01650250017008"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1016\/S0769-2617(84)80045-3"},{"key":"atypb7","doi-asserted-by":"crossref","unstructured":"Ingrand D., Briquet I., Brechon JM, et al. Lack of selection by Acyclovir (ACV) therapy of highly ACVresistant HSV2 clones detected before therapy in a patient with severe genital lesions. Ann Virol (Institut Pasteur) 1984;135E:89-97.","DOI":"10.1016\/S0769-2617(84)80042-8"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1016\/0166-0934(82)90092-1"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/131.4.423"},{"key":"atypb10","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1128\/iai.29.2.532-538.1980","volume":"29","author":"Yeager AS","year":"1980","journal-title":"Infect Immun"},{"key":"atypb11","volume-title":"The human herpesviruses. An interdisciplinary perspective","author":"Nahmias AJ","year":"1981"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(82)90097-3"},{"key":"atypb13","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1542\/peds.66.4.495","volume":"66","author":"Whitley RJ","year":"1980","journal-title":"Pediatrics"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.21.4.634"},{"key":"atypb15","first-page":"437","volume":"5","author":"Strulovitch C.","year":"1979","journal-title":"Chemother"}],"container-title":["Clinical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000992288502401118","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000992288502401118","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:26:06Z","timestamp":1777393566000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000992288502401118"}},"subtitle":["An Unusual Manifestation of Herpes Simplex Virus Infection"],"short-title":[],"issued":{"date-parts":[[1985,11]]},"references-count":15,"journal-issue":{"issue":"11","published-print":{"date-parts":[[1985,11]]}},"alternative-id":["10.1177\/000992288502401118"],"URL":"https:\/\/doi.org\/10.1177\/000992288502401118","relation":{},"ISSN":["0009-9228","1938-2707"],"issn-type":[{"value":"0009-9228","type":"print"},{"value":"1938-2707","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,11]]}}}