{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:41:40Z","timestamp":1777524100960,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[1989,7,1]],"date-time":"1989-07-01T00:00:00Z","timestamp":615254400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[1989,7]]},"abstract":"<jats:p>Childhood hypophosphatemic rickets (HR) is most often caused by a defect in renal tubular resorption of filtered phosphorus. However, HR can also be caused by secretion of a phosphaturetic factor from a tumor. The presentation of patients with the different HR syndromes may be identical. Distinguishing between the HR syndromes is essential, however, because HR caused by the renal defect requires life-long therapy with Vitamin D and phosphate replacement, but tumor-associated HR is cured by removal of the tumor. A case of hemangiopericytoma occurring in bone and causing HR is reported. Children with HR typically have normal levels of serum calcium and parathyroid hormone but very low levels of serum phosphorus. In a child with HR, the following features should prompt a thorough evaluation for a causative tumor: lack of other family members who have hypophosphatemia; presence of aminoaciduria, particularly glycinuria. Causative lesions are most commonly found in the bone or skin.<\/jats:p>","DOI":"10.1177\/000992288902800705","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T17:50:16Z","timestamp":1196099416000},"page":"321-325","source":"Crossref","is-referenced-by-count":11,"title":["Surgically Curable Hypophosphatemic Rickets"],"prefix":"10.1177","volume":"28","author":[{"given":"A.","family":"Hanukoglu","sequence":"first","affiliation":[{"name":"Division of Pediatric Endocrinology, University of Maryland School of Medicine, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.A.","family":"Chalew","sequence":"additional","affiliation":[{"name":"Division of Pediatric Endocrinology, University of Maryland School of Medicine, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.J.","family":"Sun","sequence":"additional","affiliation":[{"name":"Division of Pediatric Endocrinology, University of Maryland School of Medicine, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.D.","family":"Dorfman","sequence":"additional","affiliation":[{"name":"Division of Pediatric Endocrinology, University of Maryland School of Medicine, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.W.","family":"Bright","sequence":"additional","affiliation":[{"name":"Division of Pediatric Endocrinology, University of Maryland School of Medicine, Baltimore, Maryland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1989,7,1]]},"reference":[{"key":"atypb1","unstructured":"Rasmussen A., Anast C. Familial hypophosphatemic rickets and Vitamin D dependent rickets . In: Stanbury JB, Wyngarden JB, Fredrickson DS, Goldstein JL, Brown MS (eds). The Metabolic Basis of Inherited Disease, 5th ed. McGraw-Hill Book Co, 1983:1743-73."},{"key":"atypb2","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/0002-9343(64)90085-3","volume":"36","author":"Burnett CH","year":"1964","journal-title":"Am J Med"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(57)90333-9"},{"key":"atypb4","unstructured":"Drezner MK, Lobaugh B., Lyles KW, et al. The pathogenesis and treatment of tumor induced osteomalacia . In: Norman AW, Schaefer K, Herrath Dv, Grigoleit H-G (eds). Vitamin D Chemical, Biochemical and Clinical Endocrinology of Calcium Metabolism. New York : Walter de Gruyter, 1982:949-54."},{"key":"atypb5","first-page":"411","volume":"45","author":"Dent CE","year":"1976","journal-title":"Q J Med"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-67-1-46"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19870415)59:8<1442::AID-CNCR2820590810>3.0.CO;2-Q"},{"key":"atypb8","first-page":"1676","author":"Dent CE","year":"1964","journal-title":"Br Med J"},{"key":"atypb9","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1542\/peds.52.3.364","volume":"52","author":"Pollack JA","year":"1973","journal-title":"Pediatrics"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.59B3.893505"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1177\/000992288102001005"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-93-2-279"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(77)80444-7"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(86)80283-9"},{"key":"atypb15","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1542\/peds.52.3.432","volume":"52","author":"Harrison HE","year":"1973","journal-title":"Pediatrics"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-196711000-00001"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.30.4.328"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.38B1.204"},{"key":"atypb19","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1542\/peds.34.3.357","volume":"34","author":"Scriver CR","year":"1964","journal-title":"Pediatrics"}],"container-title":["Clinical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000992288902800705","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000992288902800705","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:22:40Z","timestamp":1777393360000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000992288902800705"}},"subtitle":["Diagnosis and Management"],"short-title":[],"issued":{"date-parts":[[1989,7]]},"references-count":19,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1989,7]]}},"alternative-id":["10.1177\/000992288902800705"],"URL":"https:\/\/doi.org\/10.1177\/000992288902800705","relation":{},"ISSN":["0009-9228","1938-2707"],"issn-type":[{"value":"0009-9228","type":"print"},{"value":"1938-2707","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,7]]}}}