{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:52:40Z","timestamp":1777524760698,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[1991,5,1]],"date-time":"1991-05-01T00:00:00Z","timestamp":673056000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[1991,5]]},"abstract":"<jats:p>Eight infants with histories of apnea and cyanosis were referred to the Southwest SIDS Research Institute for evaluation of apparent life threatening events (ALTE). All of the infants had been treated for colic with a 1:1 concentration of dimenhydrinate (Dramamine) and phenobarbital, hyoscyamine sulfate, atropine sulfate and scopolamine hydrobromide (Donnatal). The medication was pre-mixed by local pharmacists. A comprehensive work-up failed to reveal a cause for the ALTE in any infant. The Dramamine\/Donnatal mixture was withdrawn and polygraphic evaluation was conducted. Cardiorespiratory abnormalities were identified in all eight infants and significant gastroesophageal reflux (GER) was documented in four. The possibility that colic medication contributes to cardiorespiratory instability and GER in vulnerable infants requires serious consideration and further evaluation.<\/jats:p>","DOI":"10.1177\/000992289103000503","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T17:50:16Z","timestamp":1196099416000},"page":"281-285","source":"Crossref","is-referenced-by-count":22,"title":["Colic Medication and Apparent Life-Threatening Events"],"prefix":"10.1177","volume":"30","author":[{"given":"Richard A.","family":"Hardoin","sequence":"first","affiliation":[{"name":"Southwest SIDS Research Institute, Lake Jackson, Texas 77566"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith A.","family":"Henslee","sequence":"additional","affiliation":[{"name":"Southwest SIDS Research Institute, Lake Jackson, Texas 77566"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher P.","family":"Christenson","sequence":"additional","affiliation":[{"name":"Southwest SIDS Research Institute, Lake Jackson, Texas 77566"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia J.","family":"Christenson","sequence":"additional","affiliation":[{"name":"Southwest SIDS Research Institute, Lake Jackson, Texas 77566"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitchell","family":"White","sequence":"additional","affiliation":[{"name":"Southwest SIDS Research Institute, Lake Jackson, Texas 77566"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1991,5,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1542\/peds.70.1.75","volume":"70","author":"Kahn A.","year":"1982","journal-title":"Pediatr"},{"key":"atypb2","unstructured":"Behrman R., Vaughn V. Nelson Textbook of Pediatrics, 13th edition. Philadelphia, W. B. Saunders Co., 1987, p. 136-7."},{"key":"atypb3","unstructured":"Gastrointestinal Drugs: Drug Facts and Comparisons . St. Louis, J. B. Lippincott Company, 1990, p. 1373."},{"key":"atypb4","unstructured":"Gastrointestinal Drugs: Drug Facts and Comparisons . St. Louis, J. B. Lippincott Company, 1990, p. 1376."},{"key":"atypb5","unstructured":"Brown, Jr., H. Atropine, Scopolamine, and Related Antimuscarinic Drugs. Gilman A, et al. (ed). New York, Pergamon Press, Inc., 1990, p. 156."},{"key":"atypb6","unstructured":"Garrison JC Histamine, Bradykinin, 5-Hydroxytryptamine, and their Antagonists. Gilman A, et al. (ed). New York, Pergamon Press, Inc., 1990, p. 586."},{"key":"atypb7","unstructured":"Richter J. Gastroesophageal Reflux Disease. Manual of Clinical Problems in Gastroenterology . Chobanian S, Ness M (ed). Boston, Little, Brown and Co., 1988, pp. 11-12."},{"key":"atypb8","unstructured":"Antiemetic\/Antivertigo Agents: Drug Facts and Comparisons. St. Louis, J. B. Lippincott Co., 1990, p. 1075."},{"key":"atypb9","unstructured":"Martindale. The Extra Pharmacopoeia. Reynolds J (ed). London, The Pharmaceutical Press, 1989, pp. 404-6."},{"key":"atypb10","unstructured":"Sedatives and Hypnotics, Barbiturates: Drug Facts and Comparisons. St. Louis, J. B. Lippincott Company, 1990, p. 1223."},{"key":"atypb11","unstructured":"McEvoy G, (ed). AHFS Drug Information. Bethesda, MD, American Society of Hospital Pharmacists, Inc., 1990, p. 1238."}],"container-title":["Clinical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000992289103000503","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000992289103000503","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:24:14Z","timestamp":1777393454000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000992289103000503"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,5]]},"references-count":11,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1991,5]]}},"alternative-id":["10.1177\/000992289103000503"],"URL":"https:\/\/doi.org\/10.1177\/000992289103000503","relation":{},"ISSN":["0009-9228","1938-2707"],"issn-type":[{"value":"0009-9228","type":"print"},{"value":"1938-2707","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,5]]}}}