{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:36:46Z","timestamp":1777523806802,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[1993,5,1]],"date-time":"1993-05-01T00:00:00Z","timestamp":736214400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[1993,5]]},"abstract":"<jats:p>\n                    Increasing rates of congenital syphilis have been reported in recent years despite the availability of adequate therapy. In our perinatal-neonatal center, approximately 1.5 % of newborns have reactive serologic tests for syphilis.\n                    <jats:sup>1<\/jats:sup>\n                    Untreated or partly treated maternal syphilis can adversely affect neonatal outcome since the treponeme can cross the placenta at any time during pregnancy.\n                    <jats:sup>2<\/jats:sup>\n                    As a result of hematogenous placental transmission, neonatal manifestations are usually systemic and similar to the secondary stage of syphilis, and include hepatosplenomegaly, jaundice, neuro-syphilis, and skeletal changes. A case of early congenital syphilis in an extremely premature infant with primary skeletal involvement is presented.\n                  <\/jats:p>","DOI":"10.1177\/000992289303200514","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T17:50:16Z","timestamp":1196099416000},"page":"312-313","source":"Crossref","is-referenced-by-count":5,"title":["Congenital Syphilitic Skeletal Manifestations in a Premature Infant Revisited"],"prefix":"10.1177","volume":"32","author":[{"given":"Nestor B.","family":"Ilagan","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Grace Hospital Wayne State University Detroit, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burt","family":"Weyhing","sequence":"additional","affiliation":[{"name":"Department of Radiology, Grace Hospital Wayne State University Detroit, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keh-Chyang","family":"Liang","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Grace Hospital Wayne State University Detroit, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie J.","family":"Womack","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Grace Hospital Wayne State University Detroit, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seetha","family":"Shankaran","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Grace Hospital Wayne State University Detroit, Michigan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1993,5,1]]},"reference":[{"key":"atypb1","first-page":"4","volume":"29","author":"Womack SJ","year":"1991","journal-title":"PediatrRes."},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)33340-3"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1920.02350050002001"},{"key":"atypb4","unstructured":"Stowens D. Pediatric Pathology. Baltimore, MD: Williams & Wilkins; 1959:185-203."},{"key":"atypb5","unstructured":"Schulz KF, Murphy FK, Patamasucon P., et al. Congenital syphilis. In: Holmes KK, ed. Sexually Transmitted Diseases. New York, NY McGraw-Hill; 1990:821-842."},{"key":"atypb6","first-page":"1","volume":"22","author":"Pendergrass EP","year":"1929","journal-title":"Am J Roentgen Ther."},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-193606000-00008"},{"key":"atypb8","unstructured":"Stokes JH Modern Clinical Syphilology. Philadelphia, PA: WB Saunders; 1944:8."},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1007\/BF01006906"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-43-509-333"},{"key":"atypb11","volume-title":"Congenital Syphilis","author":"Nabarro D.","year":"1954"},{"key":"atypb12","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1542\/peds.1.5.601","volume":"1","author":"Platou RV","year":"1948","journal-title":"Pediatrics"},{"key":"atypb13","unstructured":"Thomas EN Syphilis: Its Course and Management. New York, NY Macmillan ; 1949:276-285."}],"container-title":["Clinical Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000992289303200514","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/000992289303200514","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T16:21:54Z","timestamp":1777393314000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/000992289303200514"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,5]]},"references-count":13,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1993,5]]}},"alternative-id":["10.1177\/000992289303200514"],"URL":"https:\/\/doi.org\/10.1177\/000992289303200514","relation":{},"ISSN":["0009-9228","1938-2707"],"issn-type":[{"value":"0009-9228","type":"print"},{"value":"1938-2707","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,5]]}}}