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Forty-one infants died (21%); standardized neurodevelopmental and functional assessments were conducted on 149 of 153 (97%) survivors at a mean age of 52 months. Five significant predictors of death were identified with logistic regression analysis: gestational age 23 to 26 weeks, intraventricular hemorrhage grades 3 or 4, male gender, five-minute Apgar \u22643, and absence of prophylactic calf lung surfactant extract. Significant predictors of neurodevelopmental morbidity included sepsis, male gender, and nonwhite race. Significant predictors of disability at age four included neurodevelopmental impairment and severe retinopathy of prematurity. Low socioeconomic status, nonwhite race and male gender were predictive of educational handicap. These findings suggest that outcomes may have distinct pathophysiologies. The role of biomedical events appears strongest for death.<\/jats:p>","DOI":"10.1177\/000992289303200903","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T17:50:16Z","timestamp":1196099416000},"page":"521-527","source":"Crossref","is-referenced-by-count":26,"title":["Predictors of Mortality, Morbidity, and Disability in a Cohort of Infants \u2264 28 Weeks' Gestation"],"prefix":"10.1177","volume":"32","author":[{"given":"Michael E.","family":"Msall","sequence":"first","affiliation":[{"name":"Associate Professor, Departments of Pediatrics and Rehabilitation Medicine, SUNY at Buffalo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Germaine M.","family":"Buck","sequence":"additional","affiliation":[{"name":"Clinical Assistant Professor, Department of Social and Preventive Medicine, SUNY at Buffalo"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian 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