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All children had echocardiographic and Doppler measurements indicative of impaired ventricular function which significantly improved during the course of hospitalization, as evidenced in part by the change in fractional shortening (P= 0.015), mean velocity of circumferential fiber shortening (P= 0.038), and systolic time interval (P = 0.030). We conclude that children with primary third-degree malnutrition not only have cardiac muscle wasting, but also have inherent ventricular dysfunction as the result of severe malnutrition that responds to nutritional therapy. Particular care with fluid administration is imperative in the first week of therapy, when heart function is the most compromised.<\/jats:p>","DOI":"10.1177\/000992289403300304","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T17:50:16Z","timestamp":1196099416000},"page":"147-154","source":"Crossref","is-referenced-by-count":35,"title":["Cardiac Function in Malnourished Children"],"prefix":"10.1177","volume":"33","author":[{"given":"Chalie","family":"Phornphatkul","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Chiang Mai University Medical School, Chiang Mai, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yupada","family":"Pongprot","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Chiang Mai University Medical School, Chiang Mai, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Suskind","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Louisiana State University Medical School, New Orleans, Louisiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Varghese","family":"George","sequence":"additional","affiliation":[{"name":"Department of Biometry and Genetics, Louisiana State University School Medical Center, New Orleans, Louisiana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Fuchs","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Chiang Mai University Medical School, Chiang Mai, Thailand, Department of Pediatrics, Louisiana State University Medical School, New Orleans, Louisiana"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1994,3,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1542\/peds.66.6.972","volume":"66","author":"Chase PH","year":"1980","journal-title":"Pediatrics"},{"key":"atypb2","unstructured":"Fuchs GJ Secondary malnutrition in children. 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