{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:52:35Z","timestamp":1777524755128,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[1997,5,1]],"date-time":"1997-05-01T00:00:00Z","timestamp":862444800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[1997,5]]},"abstract":"<jats:p>The purpose of this study was to determine whether cholesterol screening and nutritional counseling can reduce cholesterol concentrations in populations of otherwise unrecognized hypercholesterolemic children. A large pediatric practice in Parma Heights, Ohio, has conducted cholesterol surveillance of children over 2 years of age since 1986. The importance of cholesterol and other recognized risk factors for the progression of atherosclerosis is discussed with all families, and the American Heart Association's Step-One diet is recommended. The present study examines data from a cohort of 894 children (473 boys, 421 girls) who had cholesterol concentrations above 185 mg\/dL (4.79 mmol\/L) (the 90th percentile) at baseline and, after counseling, had a repeat measurement an average of 2.2 years later. Their mean ages were 7 years at the first testing and 9.2 years at the second. Children who had cholesterol concentrations above 200 mg\/dL (5.18 mmol\/L) (the 95th percentile) had lipoprotein profiles done, and if their LDL cholesterol exceeded 130 mg\/dL (3.37 mmol\/L) (the 95th percentile), they were referred to a nutritionist, and family members were advised to have their blood lipids analyzed.<\/jats:p>\n                  <jats:p>Mean cholesterol concentration for all 894 children over this time period decreased by 9.4% (19.5 mg\/dL [0.51 mmol\/L]; 95% CI = 17.5 mg\/dL [0.45 mmol\/L] to 21.5 mg\/dL [0.56 mmol\/L]; P&lt;0.001). A similar decrease of 8.6% (16.6 mg\/dL [0.43 mmol\/L]; 95% CI = 14.0 mg\/dL [0.36 mmol\/L] to 19.3 mg\/dL [0.50 mmol\/L]; P&lt;0.001) was observed for the 463 children who had initial cholesterol concentrations between 185 and 200 mg\/dL (4.79 and 5.18 mmol\/L) and who therefore received a less intense intervention. Cholesterol concentrations in groups of otherwise unidentified hypercholesterolemic children can be significantly reduced as a result of cholesterol screening and nutritional counseling in a pediatric practice setting.<\/jats:p>","DOI":"10.1177\/000992289703600503","type":"journal-article","created":{"date-parts":[[2007,6,21]],"date-time":"2007-06-21T21:21:41Z","timestamp":1182460901000},"page":"267-272","source":"Crossref","is-referenced-by-count":6,"title":["Influence of Cholesterol Screening and Nutritional Counseling in Reducing Cholesterol Levels in Children"],"prefix":"10.1177","volume":"36","author":[{"given":"Jill","family":"Fitch","sequence":"first","affiliation":[{"name":"Division of Pediatrics, A120, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard E.","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas S.","family":"Moodie","sequence":"additional","affiliation":[{"name":"Division of Pediatrics, The Cleveland Clinic Foundation, Cleveland, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Secic","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Epidemiology, The Cleveland Clinic Foundation, Cleveland, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1997,5,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1990.03450230075032"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1991.03460220091039"},{"key":"atypb3","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1542\/peds.89.3.509","volume":"89","author":"Lauer R","year":"1992","journal-title":"Pediatrics"},{"key":"atypb4","first-page":"19","volume":"11","author":"Gidding S","year":"1994","journal-title":"Contemp Pediatr"},{"key":"atypb5","first-page":"751","volume":"84","author":"Garcia RE","year":"1989","journal-title":"Pediatrics"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1990.03450230070031"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(05)82403-5"},{"key":"atypb8","first-page":"309","volume":"82","author":"Lauer M","year":"1988","journal-title":"Pediatrics"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1016\/0091-7435(85)90036-2"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1987.03390160062027"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1984.03340270029025"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1986.03380200061022"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9150(87)90234-6"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198601163140302"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1990.03450230054029"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1990.03440090079031"},{"key":"atypb17","first-page":"17","volume":"8","author":"Schuman A","year":"1991","journal-title":"Contemp Pediatr"},{"issue":"2","key":"atypb18","first-page":"4","volume":"76","author":"Castelli WP","year":"1984","journal-title":"AmJMed"},{"key":"atypb19","unstructured":"19. National Cholesterol Education Program. Report of the Expert Panel on Blood Cholesterol Levels in Children and Adolescents. 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