{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:47:21Z","timestamp":1777524441192,"version":"3.51.4"},"reference-count":31,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[1999,9,1]],"date-time":"1999-09-01T00:00:00Z","timestamp":936144000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clin Pediatr (Phila)"],"published-print":{"date-parts":[[1999,9]]},"abstract":"<jats:p>The objective of the study was to develop clinical screening criteria to diagnose infants with intraventricular hemorrhage (IVH) and cystic periventricular leukomalacia (PVL). We performed a case-control investigation of two cohorts of very-low-birth-weight infants (n=505, combined cohorts). Univariate and multivariate analyses were performed from data obtained in cohort 1 to develop screening criteria for IVH and cystic PVL. The screening criteria were then applied to cohort 2. The screening criteria for IVH had a sensitivity of only 51 %, a specificity of 62%, a positive predictive value of 31 %, and a negative predictive value of 79%. Screening criteria for cystic PVL had a sensitivity of only 22%, a specificity of 58% a positive predictive value of 2%, and a negative predictive value of 95%. These data suggest that using clinical criteria to determine which infants should receive screening cranial sonography for IVH and cystic PVL would miss a substantial number of infants with these conditions. Clin Pediatr. 1999;38:503-509<\/jats:p>","DOI":"10.1177\/000992289903800901","type":"journal-article","created":{"date-parts":[[2007,11,26]],"date-time":"2007-11-26T17:50:16Z","timestamp":1196099416000},"page":"503-509","source":"Crossref","is-referenced-by-count":7,"title":["Cranial Sonography in Very-Low-Birth-Weight Infants: Do All Infants Need to Be Screened?"],"prefix":"10.1177","volume":"38","author":[{"given":"David A.","family":"Paul","sequence":"first","affiliation":[{"name":"Section of Neonatal Medicine, Department of Pediatrics, Christiana Care Health System, Newark, DE, Department of Pediatrics, Thomas Jefferson Medical College, Philadelphia, PA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen A.","family":"Pearlman","sequence":"additional","affiliation":[{"name":"Section of Neonatal Medicine, Department of Pediatrics, Christiana Care Health System, Newark, DE, Department of Pediatrics, Thomas Jefferson Medical College, Philadelphia, 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