{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T05:11:30Z","timestamp":1778562690872,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2017,11,7]],"date-time":"2017-11-07T00:00:00Z","timestamp":1510012800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Hosp Pharm"],"published-print":{"date-parts":[[2018,6]]},"abstract":"<jats:p>Background: The use of epidural anesthesia has been shown to improve outcomes in the postoperative setting. To minimize risk of complications, avoiding certain medications with epidural anesthesia is advised. Objective: This study sought to determine the role of a computerized clinical decision support module implemented into the computerized physician order entry (CPOE) system on the incidence of administration of medications known to increase complications with epidural anesthesia. Methods: This study was a retrospective cohort chart review in adult patients receiving epidural anesthesia for at least 1 day. Patients were identified retrospectively and divided into 2 cohorts, those receiving an epidural 3 months prior to initiation of the module and those receiving an epidural 3 months following implementation. The primary end point was incidence of inappropriate medication administration before and after implementation. Complications of therapy were collected as secondary end points. Results: There was a reduction in the incidence of inappropriate medication administration in the postimplementation group versus the preimplementation group (6.3% vs 12.8%) although statistical significance was not achieved. In addition, the incidence of enoxaparin administration was significantly lower postimplementation than the preimplementation (0% vs 3.9%). There were no significant differences in other complications of therapy. Conclusions: This study demonstrated that application of decision support for this high-risk procedural population was able to eliminate the incidence of the most common inappropriate medication for epidural analgesia, enoxaparin. A reduction in incidence of other inappropriate medications was also observed; however, statistical significance was not reached. The use of computerized clinical decision support can be a powerful tool in reducing or ameliorating medication errors, and further study will be required to determine the most appropriate and effective implementation strategies.<\/jats:p>","DOI":"10.1177\/0018578717741392","type":"journal-article","created":{"date-parts":[[2017,11,7]],"date-time":"2017-11-07T04:52:24Z","timestamp":1510030344000},"page":"170-176","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["The Role of Computerized Clinical Decision Support in Reducing Inappropriate Medication Administration During Epidural Therapy"],"prefix":"10.1177","volume":"53","author":[{"given":"Jonathon D.","family":"Pouliot","sequence":"first","affiliation":[{"name":"Lipscomb University College of Pharmacy and Health Sciences, Nashville, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin B.","family":"Neal","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bob L.","family":"Lobo","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fred","family":"Hargrove","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajnish K.","family":"Gupta","sequence":"additional","affiliation":[{"name":"Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,11,7]]},"reference":[{"key":"bibr1-0018578717741392","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.321.7275.1493"},{"key":"bibr2-0018578717741392","doi-asserted-by":"publisher","DOI":"10.1097\/00115550-200411000-00004"},{"key":"bibr3-0018578717741392","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e31818ec946"},{"key":"bibr4-0018578717741392","doi-asserted-by":"publisher","DOI":"10.1213\/01.ane.0000258740.17193.ec"},{"key":"bibr5-0018578717741392","doi-asserted-by":"publisher","DOI":"10.1097\/AAP.0b013e3181c15c70"},{"key":"bibr6-0018578717741392","doi-asserted-by":"publisher","DOI":"10.1097\/01.aco.0000245282.45529.b0"},{"key":"bibr7-0018578717741392","doi-asserted-by":"publisher","DOI":"10.1097\/EJA.0b013e32833f6f6f"},{"key":"bibr8-0018578717741392","doi-asserted-by":"publisher","DOI":"10.1590\/S1516-31802011000100004"},{"key":"bibr9-0018578717741392","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.12.1409"},{"key":"bibr10-0018578717741392","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-008-0504-5"},{"key":"bibr11-0018578717741392","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-6773.2007.00751.x"},{"key":"bibr12-0018578717741392","doi-asserted-by":"publisher","DOI":"10.1097\/MJT.0b013e31825a3631"},{"key":"bibr13-0018578717741392","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"}],"container-title":["Hospital Pharmacy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0018578717741392","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0018578717741392","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0018578717741392","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:36:51Z","timestamp":1777451811000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0018578717741392"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,7]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,6]]}},"alternative-id":["10.1177\/0018578717741392"],"URL":"https:\/\/doi.org\/10.1177\/0018578717741392","relation":{},"ISSN":["0018-5787","1945-1253"],"issn-type":[{"value":"0018-5787","type":"print"},{"value":"1945-1253","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,7]]}}}