{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T08:54:44Z","timestamp":1779180884795,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2018,5,29]],"date-time":"2018-05-29T00:00:00Z","timestamp":1527552000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Hosp Pharm"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:p>Background: Intracavernosal injection of phenylephrine is a commonly used therapy for ischemic priapism and is typically well tolerated with few severe adverse side effects. We report a case of intracranial hemorrhage related to hypertensive emergency due to intracavernosal phenylephrine. Case Report: A 43-year-old Caucasian man with history of hypertension, diabetes mellitus type I, end-stage renal disease status post a combination kidney-pancreas transplant, and recurrent idiopathic priapism presented to emergency department with an episode of priapism. His home medications were lisinopril, metoprolol tartrate, mycophenolate mofetil, prednisone, sulfamethoxazole-trimethoprim, and tacrolimus. After local injection of 2 rounds (1 hour apart) of 100 \u00b5g phenylephrine into each corpus cavernosa, priapism resolved. Within 5 minutes, the patient had headaches, dyspnea, and excruciating chest pain. His blood pressure (BP) was noted to be 240\/130 mm Hg but normalized spontaneously within few minutes. During this period, he developed new-onset right arm and leg weakness and found to have intracranial hemorrhage in the midbrain. Conclusion: A careful review for pharmacologic interactions should be performed prior to intracavernosal phenylephrine administration, and close monitoring should occur after its administration.<\/jats:p>","DOI":"10.1177\/0018578718778230","type":"journal-article","created":{"date-parts":[[2018,5,29]],"date-time":"2018-05-29T05:48:31Z","timestamp":1527572911000},"page":"186-189","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["A Case Report of Hypertensive Emergency and Intracranial Hemorrhage Due to Intracavernosal Phenylephrine"],"prefix":"10.1177","volume":"54","author":[{"given":"Raga Deepak Reddy","family":"Palagiri","sequence":"first","affiliation":[{"name":"University of Arkansas for Medical Sciences, Little Rock, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kshitij","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"University of Arkansas for Medical Sciences, Little Rock, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anusha","family":"Jillella","sequence":"additional","affiliation":[{"name":"University of Arkansas for Medical Sciences, Little Rock, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Drayton A.","family":"Hammond","sequence":"additional","affiliation":[{"name":"Rush University, Chicago, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,5,29]]},"reference":[{"key":"bibr1-0018578718778230","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2013.03.118"},{"key":"bibr2-0018578718778230","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(01)00941-4"},{"key":"bibr3-0018578718778230","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsxm.2016.09.010"},{"key":"bibr4-0018578718778230","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2005.46.2.305"},{"key":"bibr5-0018578718778230","doi-asserted-by":"publisher","DOI":"10.4103\/1658-354X.101224"},{"issue":"1","key":"bibr6-0018578718778230","first-page":"S1","volume":"19","author":"Podolej GS","year":"2017","journal-title":"Emerg Med Pract"},{"key":"bibr7-0018578718778230","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-6109.2005.00140.x"},{"key":"bibr8-0018578718778230","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)65841-7"},{"key":"bibr9-0018578718778230","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000087608.07371.ca"},{"key":"bibr10-0018578718778230","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)66575-3"},{"key":"bibr11-0018578718778230","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2007.10.024"},{"key":"bibr12-0018578718778230","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-6109.2007.00715.x"},{"issue":"3","key":"bibr13-0018578718778230","first-page":"167","volume":"21","author":"Srivastava RD","year":"1977","journal-title":"Indian J Physiol Pharmacol"},{"key":"bibr14-0018578718778230","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1667-10.2010"},{"key":"bibr15-0018578718778230","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1981.154"}],"container-title":["Hospital Pharmacy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0018578718778230","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0018578718778230","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0018578718778230","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:38:29Z","timestamp":1777451909000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0018578718778230"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,29]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1177\/0018578718778230"],"URL":"https:\/\/doi.org\/10.1177\/0018578718778230","relation":{},"ISSN":["0018-5787","1945-1253"],"issn-type":[{"value":"0018-5787","type":"print"},{"value":"1945-1253","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,29]]}}}