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In this article we discuss a case of DPP-4i associated BP and we provide an updated review of the current knowledge regarding this emerging entity. Use of DPP-4i, particularly vildagliptin, was found to significantly increase the risk of BP. BP180 would be in the center of the aberrant immune response. DPP-4i induced BP is thought to be associated with male gender, mucosal involvement, and milder inflammatory phenotype especially in Asian population. Generally, patients may not remit fully after DPP-4i withdrawal only and require either topical or systemic glucocorticoid courses.<\/jats:p>","DOI":"10.1177\/00185787231151861","type":"journal-article","created":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T01:00:06Z","timestamp":1675990806000},"page":"357-362","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Bullous Pemphigoid Associated With Dipeptidyl Peptidase-4 Inhibitors: A Case Report and Review of Current Evidence"],"prefix":"10.1177","volume":"58","author":[{"given":"Faten","family":"Hadjkacem","sequence":"first","affiliation":[{"name":"University of Sfax, Sfax, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0291-0879","authenticated-orcid":false,"given":"Hamdi","family":"Frikha","sequence":"additional","affiliation":[{"name":"University of Sfax, Sfax, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khouloud","family":"Boujelben","sequence":"additional","affiliation":[{"name":"University of Sfax, Sfax, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiraz","family":"Chaari","sequence":"additional","affiliation":[{"name":"University of Sfax, Sfax, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emna","family":"Mnif","sequence":"additional","affiliation":[{"name":"University of Sfax, Sfax, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abderrahmen","family":"Masmoudi","sequence":"additional","affiliation":[{"name":"University of Sfax, Sfax, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tahia","family":"Boudawara","sequence":"additional","affiliation":[{"name":"University of Sfax, Sfax, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamida","family":"Turki","sequence":"additional","affiliation":[{"name":"University of Sfax, Sfax, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Abid","sequence":"additional","affiliation":[{"name":"University of Sfax, Sfax, Tunisia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,2,9]]},"reference":[{"key":"bibr1-00185787231151861","unstructured":"Baigrie D, Nookala V. 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