{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:45:42Z","timestamp":1790635542240,"version":"4.1.0"},"reference-count":19,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,4,27]],"date-time":"2024-04-27T00:00:00Z","timestamp":1714176000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Hosp Pharm"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:p>\n                    <jats:bold>Background:<\/jats:bold>\n                    In 2002, the Centers for Medicare and Medicaid Services (CMS) in collaboration with the Centers for Disease Control and Prevention (CDC) established the\n                    <jats:italic toggle=\"yes\">Surgical Infection Prevention<\/jats:italic>\n                    (SIP) project for the purposes of developing and standardizing quality improvement measures known to reduce the rates of post-operative surgical site infections (SSIs). Four years later the\n                    <jats:italic toggle=\"yes\">Surgical Care Improvement Project<\/jats:italic>\n                    (SCIP), an expansion of SIP, was published in governmental\n                    <jats:italic toggle=\"yes\">Specifications Manual for National Inpatient Quality Measures and<\/jats:italic>\n                    provided several additional initiatives applicable to the perioperative period. Central to both projects are the assurance of the timeliness, selection, and duration of peri-operative surgical prophylactic antibiotics. In support of this objective, various medical associations, such as the American Society of Health-System Pharmacists (ASHP) and the Infectious Diseases Society of America (IDSA), have developed the\n                    <jats:italic toggle=\"yes\">Clinical Practice Guidelines for Antimicrobial Prophylaxis in Surgery<\/jats:italic>\n                    . To ensure compliance with quality measures, hospitals are required to report data to the\n                    <jats:italic toggle=\"yes\">Physicians Quality Reporting System<\/jats:italic>\n                    , which is then reviewed by CMS for reimbursement purposes and to measure hospital performance. To maintain optimal standards of care and satisfy all core measures, it is expected that patients undergoing most categories of surgical procedures receive prophylactic antibiotics. We recognized that patients already being administered antimicrobial therapy as treatment for the condition requiring the surgery not uncommonly also were prescribed unwarranted and redundant pre-operative antibiotics. Our study was meant to quantify such antibiotic redundancy, which only risks the development of antimicrobial resistance and adverse events, to bolster our and other hospitals antimicrobial stewardship programs.\n                    <jats:bold>Methods:<\/jats:bold>\n                    A retrospective analysis of computerized hospital records over a one-month period of time (November 2022) was conducted focusing on hospital admissions that involved surgical operative procedures. Only those patients who had received a pre-operative surgical prophylactic antibiotic were included in the analysis.\n                    <jats:bold>Results:<\/jats:bold>\n                    Of the 92 surgeries that fulfilled the inclusion criteria, 38 (41.3%) were performed on patients who were already receiving therapeutic antibiotics for more than 24\u2009hours targeted to treat the infection for which they were undergoing surgery. These included laparoscopic cholecystectomy (24), appendectomy (12), wound debridement (12), and soft tissue incision and drainage procedures (9), comprising nearly 50% of each type of these operations performed during the study time period.\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    These findings demonstrate a clear opportunity to strengthen both our, and presumably other, hospitals antimicrobial stewardship programs. Together with physician education, granting the pharmacy the ability to cancel unnecessary and redundant surgical prophylactic antibiotics would conceivably be of great benefit.\n                  <\/jats:p>","DOI":"10.1177\/00185787241230079","type":"journal-article","created":{"date-parts":[[2024,4,27]],"date-time":"2024-04-27T04:24:10Z","timestamp":1714191850000},"page":"460-464","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["When Antimicrobial Treatment and Surgical Prophylaxis Collide: A Stewardship Opportunity"],"prefix":"10.1177","volume":"59","author":[{"given":"Priscila","family":"Fiallo","sequence":"first","affiliation":[{"name":"Department of Medicine, Wellington Regional Medical Center, Wellington, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Williams","sequence":"additional","affiliation":[{"name":"Department of Medicine, Wellington Regional Medical Center, Wellington, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0836-5947","authenticated-orcid":false,"given":"Larry M.","family":"Bush","sequence":"additional","affiliation":[{"name":"Department of Medicine, Wellington Regional Medical Center, Wellington, FL, USA"},{"name":"Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, USA"},{"name":"University of Miami-Miller School of Medicine, Palm Beach County, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,4,27]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.5588\/pha.21.0027"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.2146\/ajhp120568"},{"key":"e_1_3_2_4_2","first-page":"784","article-title":"Centers for disease control and prevention guideline for the prevention of surgical site infection","volume":"152","author":"Berrios-Torres SI","year":"2017","unstructured":"Berrios-Torres SI, Umscheid CA, Bratzler DW, et al. Centers for disease control and prevention guideline for the prevention of surgical site infection. JAMA. 2017;152:784-791.","journal-title":"JAMA"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2023.67"},{"key":"e_1_3_2_6_2","first-page":"3","article-title":"Approved: new antimicrobial stewardship standard","volume":"36","author":"Joint Commission on Hospital Accreditation","year":"2016","unstructured":"Joint Commission on Hospital Accreditation. Approved: new antimicrobial stewardship standard. Jt Comm Perspect. 2016;36:3-4.","journal-title":"Jt Comm Perspect"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciy921"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2010.083"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1306801"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1086\/501620"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e318199f202"},{"key":"e_1_3_2_12_2","volume":"65","author":"Announcement: get smart about antibiotics week\u2014 November 14\u201320, 2016","year":"2016","unstructured":"Announcement: get smart about antibiotics week\u2014 November 14\u201320, 2016. MMWR Morb MortalWkly Rep 2016; 65:1240.","journal-title":"MMWR Morb MortalWkly Rep"},{"key":"e_1_3_2_13_2","first-page":"194","article-title":"Centers for Disease Control and Prevention (CDC). Vital signs: improving antibiotic use among hospitalized patients","volume":"63","author":"Fridkin S","year":"2014","unstructured":"Fridkin S, Baggs J, Fagan R, et al. Centers for Disease Control and Prevention (CDC). Vital signs: improving antibiotic use among hospitalized patients. MMWR Morb Mortal Wkly Rep. 2014;63:194-200.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_3_2_14_2","doi-asserted-by":"crossref","unstructured":"Approved: New Antimicrobial Stewardship Standard Approved: New Antimicrobial Stewardship Standard. JT.Comm Perspect. 2016;36(7):1 3-4.","DOI":"10.1016\/j.ptdy.2017.02.035"},{"key":"e_1_3_2_15_2","unstructured":"CDC. Core Elements of Hospital Antibiotic Stewardship Programs. US Department of Health and Human Services CDC; 2019. https:\/\/www.cdc.gov\/antibiotic-use\/core-elements\/hospital.html"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2015.01.006"},{"key":"e_1_3_2_17_2","first-page":"1","article-title":"Optimizing prophylactic antibiotic practice for cardiothoracic surgery by pharmacists\u2019effects","volume":"95","author":"Zhou L","year":"2016","unstructured":"Zhou L, Ma J, Gao J, et al. Optimizing prophylactic antibiotic practice for cardiothoracic surgery by pharmacists\u2019effects. Medicine. 2016;95:1-9.","journal-title":"Medicine"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw217"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix065"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix530"}],"container-title":["Hospital Pharmacy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00185787241230079","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00185787241230079","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00185787241230079","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T11:02:56Z","timestamp":1784545376000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00185787241230079"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,27]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1177\/00185787241230079"],"URL":"https:\/\/doi.org\/10.1177\/00185787241230079","relation":{},"ISSN":["0018-5787","1945-1253"],"issn-type":[{"value":"0018-5787","type":"print"},{"value":"1945-1253","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,27]]}}}