{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T12:01:42Z","timestamp":1784548902208,"version":"3.55.0"},"reference-count":12,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T00:00:00Z","timestamp":1735516800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Hosp Pharm"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:p>Amid the early 2020 SARS-CoV-2 crisis, severe hand sanitizer shortages led to OMS local production recommendations, inviting a diverse array of alcohol producers to contribute. However, not all followed mandatory controls for API-grade alcohol. We conducted a study to ensure the safety of the received alcohols, focusing on methanol and acetaldehyde levels. All samples were well below Ph. Eur guidelines, affirming their safety for use. Furthermore, no additional impurities were detected, reinforcing the quality and safety of the assessed hand sanitizers. Our findings, amidst the scarcity of the SARS-CoV-2 era, highlight the importance of rigorous safety assessments during local hand sanitizer production.<\/jats:p>","DOI":"10.1177\/00185787241309254","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T00:54:11Z","timestamp":1735606451000},"page":"300-302","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Ensuring the Safety of Locally Sourced Alcohols for Hand Sanitizer Production During the SARS-CoV-2 Crisis: A Comprehensive Impurity Analysis"],"prefix":"10.1177","volume":"60","author":[{"given":"Camille","family":"Jurado","sequence":"first","affiliation":[{"name":"Toulouse University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zoubeir","family":"Ramjaun","sequence":"additional","affiliation":[{"name":"Toulouse University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Souleiman","family":"El Balkhi","sequence":"additional","affiliation":[{"name":"University Hospital Centre of Limoges, Limoges, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franck","family":"Saint-Marcoux","sequence":"additional","affiliation":[{"name":"University Hospital Centre of Limoges, Limoges, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Alonso","sequence":"additional","affiliation":[{"name":"Toulouse University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Sophie","family":"Salabert","sequence":"additional","affiliation":[{"name":"Toulouse University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanny","family":"Durand","sequence":"additional","affiliation":[{"name":"Toulouse University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laetitia","family":"Caturla","sequence":"additional","affiliation":[{"name":"Toulouse University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9266-4941","authenticated-orcid":false,"given":"David","family":"Metsu","sequence":"additional","affiliation":[{"name":"Montauban Hospital, Montauban, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie","family":"Gardes","sequence":"additional","affiliation":[{"name":"Toulouse University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Quelven-Bertin","sequence":"additional","affiliation":[{"name":"Toulouse University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Cestac","sequence":"additional","affiliation":[{"name":"Toulouse University Hospital, Toulouse, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,12,30]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/1745-6673-3-26"},{"key":"e_1_3_3_3_2","unstructured":"World Health Organization. World Health Organization - 2020 - WHO Interim Recommendation 1 April 2020. 2020. Accessed December 23 2024. https:\/\/www.who.int\/publications\/m\/item\/interim-recommendations-on-obligatory-hand-hygiene-against-transmission-of-covid-19"},{"key":"e_1_3_3_4_2","volume-title":"WHO Guidelines on Hand Hygiene in Health Care: First Global Patient Safety Challenge: Clean Care is Safer Care","author":"World Health Organization","year":"2009","unstructured":"World Health Organization. WHO Guidelines on Hand Hygiene in Health Care: First Global Patient Safety Challenge: Clean Care is Safer Care, Chapter 12. World Health Organization, Patient Safety; 2009."},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2020.119431"},{"key":"e_1_3_3_6_2","volume-title":"European Pharmacopoeia","author":"European Directorate for the Quality of Medicines & HealthCare (EDQM)","year":"2023","unstructured":"European Directorate for the Quality of Medicines & HealthCare (EDQM). Ethanol 96% v\/v. In: European Pharmacopoeia. 11th ed. Strasbourg, France: Council of Europe; 2023.","edition":"11"},{"key":"e_1_3_3_7_2","unstructured":"Governement of Canada Department of Health. Technical-grade ethanol for the manufacture of hand sanitizers and hard-surface disinfectants during the COVID-19 pandemic: Risk assessment summary report - Canada.ca. 2022. Accessed December 23 2024. https:\/\/www.canada.ca\/en\/health-canada\/services\/drugs-health-products\/natural-non-prescription\/legislation-guidelines\/covid19-technical-grade-ethanol-hand-sanitizer\/risk-assessment-summary-report.html"},{"key":"e_1_3_3_8_2","unstructured":"METHANOL ICSC: 0057 (May 2018) Methyl alcohol Carbinol Wood alcohol Methyl hydrate CAS #: 67-56-1 UN #: 1230 EC Number: 200-659-6 ACUTE HAZARDS PREVENTION WHO\/IPCS INCHEM Database Methanol document. Accessed December 23 2024. http:\/\/www.inchem.org\/documents\/icsc\/icsc\/eics0057.htm"},{"key":"e_1_3_3_9_2","volume-title":"Opinion on Acetaldehyde","author":"European Commission; Directorate General for Health & Consumers","year":"2012","unstructured":"European Commission; Directorate General for Health & Consumers. Opinion on Acetaldehyde. European Commission; 2012."},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e31822f09c0"},{"key":"e_1_3_3_11_2","unstructured":"Food and Drug Administration. FDA advises consumers not to use hand sanitizer products manufactured by Eskbiochem. 2020. Accessed Decemeber 23 2024. https:\/\/www.fda.gov\/drugs\/drug-safety-and-availability\/fda-advises-consumers-not-use-hand-sanitizer-products-manufactured-eskbiochem"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/15563650.2021.1895202"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2021.102050"}],"container-title":["Hospital Pharmacy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00185787241309254","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00185787241309254","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00185787241309254","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T11:04:51Z","timestamp":1784545491000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00185787241309254"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,30]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["10.1177\/00185787241309254"],"URL":"https:\/\/doi.org\/10.1177\/00185787241309254","relation":{},"ISSN":["0018-5787","1945-1253"],"issn-type":[{"value":"0018-5787","type":"print"},{"value":"1945-1253","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,30]]}}}