{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T06:33:45Z","timestamp":1772778825082,"version":"3.50.1"},"reference-count":57,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T00:00:00Z","timestamp":1711584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000104","name":"National Aeronautics and Space Administration","doi-asserted-by":"publisher","award":["80NSSC18K1572"],"award-info":[{"award-number":["80NSSC18K1572"]}],"id":[{"id":"10.13039\/100000104","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Hum Factors"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p> To evaluate a personalized adaptive training program designed for stress prevention using graduated stress exposure. <\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p> Astronauts in the high-risk space mission environment are prone to performance-impairing stress responses, making preemptive stress inoculation essential for their training. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p> This work developed an adaptive virtual reality-based system that adjusts environmental stressors based on real-time stress indicators to optimize training stress levels. Sixty-five healthy subjects underwent task training in one of three groups: skill-only (no stressors), fixed-graduated (prescheduled stressor changes), and adaptive. Psychological (subjective stress, task engagement, distress, worry, anxiety, and workload) and physiological (heart rate, heart rate variability, blood pressure, and electrodermal activity) responses were measured. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p> The adaptive condition showed a significant decrease in heart rate and a decreasing trend in heart rate variability ratio, with no changes in the other training conditions. Distress showed a decreasing trend for the graduated and adaptive conditions. Task engagement showed a significant increase for adaptive and a significant decrease for the graduated condition. All training conditions showed a significant decrease in worry and anxiety and a significant increase in the other heart rate variability metrics. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p> Although all training conditions mitigated some stress, the preponderance of trial effects for the adaptive condition supports that it is more successful at decreasing stress. <\/jats:p><\/jats:sec><jats:sec><jats:title>Application<\/jats:title><jats:p> The integration of real-time personalized stress exposure within a VR-based training program not only prepares individuals for high-stress situations by preemptively mitigating stress but also customizes stressor levels to the crew member\u2019s current state, potentially enhancing resilience to future stressors. <\/jats:p><\/jats:sec>","DOI":"10.1177\/00187208241241968","type":"journal-article","created":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T13:08:35Z","timestamp":1711631315000},"page":"5-20","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Virtual Reality Adaptive Training for Personalized Stress Inoculation"],"prefix":"10.1177","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4170-9986","authenticated-orcid":false,"given":"Tor","family":"Finseth","sequence":"first","affiliation":[{"name":"Iowa State University, USA"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6386-4787","authenticated-orcid":false,"given":"Michael C.","family":"Dorneich","sequence":"additional","affiliation":[{"name":"Iowa State University, USA"}]},{"given":"Nir","family":"Keren","sequence":"additional","affiliation":[{"name":"Iowa State University, USA"}]},{"given":"Warren D.","family":"Franke","sequence":"additional","affiliation":[{"name":"Iowa State University, USA"}]},{"given":"Stephen","family":"Vardeman","sequence":"additional","affiliation":[{"name":"Iowa State University, USA"}]}],"member":"179","published-online":{"date-parts":[[2024,3,28]]},"reference":[{"key":"bibr1-00187208241241968","volume-title":"A methodology for training international space station crews to respond to on-orbit emergencies (No. 2009-01-2446)","author":"Balmain C.","year":"2009"},{"key":"bibr2-00187208241241968","doi-asserted-by":"publisher","DOI":"10.1145\/3301498"},{"key":"bibr3-00187208241241968","doi-asserted-by":"publisher","DOI":"10.1080\/08995605.2021.1897494"},{"key":"bibr4-00187208241241968","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.310.6973.170"},{"issue":"1","key":"bibr5-00187208241241968","first-page":"1017","volume":"49","author":"Braithwaite J. 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