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Although it may present at any age, adolescence to early adulthood is the most common age of onset, and females are affected twice as much as males. Rumination is a specific known risk factor for the onset, severity, prolongation, and relapse of depression. Relapse prevention in recurrent depression is a significant public health problem, and antidepressants are the current first-line treatment approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>This study aims to evaluate the efficacy of mindfulness-based cognitive therapy in alleviating depressive symptoms, reducing rumination, and preventing relapse among depressive patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method:<\/jats:title>\n                    <jats:p>\n                      This randomized controlled trial was conducted with 101 population of 101 consisting of adult patients with three or more previous episodes. Participants were randomly assigned to Mindfulness-Based Cognitive Therapy (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200950) and Control Group (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u200951) using randomized sampling. The Mindfulness-Based Cognitive Therapy group received 8-week group training sessions including meditation exercises, psycho-education and group discussions. The assessment was done at baseline, post-treatment, and 2-month follow-up. Analysis was done using SPSS software (V 22).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Result:<\/jats:title>\n                    <jats:p>\n                      The results showed that there were no significant differences between the groups on depression relapse (\u03c7\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.002;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.99). However, there is a statistically significant reduction in depressive symptoms mean score level in the MBCT group [\n                      <jats:italic toggle=\"yes\">F<\/jats:italic>\n                      (2, 37)\u2009=\u20096.878,\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u2009.003]. Moreover, there is a statistically significant reduction in rumination score in the MBCT group\n                      <jats:italic toggle=\"yes\">[F<\/jats:italic>\n                      (2,37)\u2009=\u200936.021;\n                      <jats:italic toggle=\"yes\">p<\/jats:italic>\n                      \u2009=\u20090.02].\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The findings showed that MBCT appears efficacious in reducing depressive symptoms and rumination. However, MBCT did not further reduce their risk for relapse\/recurrence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00207640251405457","type":"journal-article","created":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T02:23:01Z","timestamp":1767061381000},"page":"1225-1238","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Evaluating the Efficacy of Mindfulness-Based Cognitive Therapy in Alleviating Depressive Symptoms, Reducing Rumination, and Preventing Relapse Among the Institutionalized Patients in Nigeria: A Randomized Controlled Trial"],"prefix":"10.1177","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1450-1581","authenticated-orcid":false,"given":"Zulkiflu Musa","family":"Argungu","sequence":"first","affiliation":[{"name":"Department of Nursing, College of Applied Sciences, Almaarefa University, Diriyah, 13713, Riyadh, Saudi Arabia"},{"name":"Research Center, Deanship of Scientific Research and Post-Graduate Studies, AlMaarefa University, Diriyah, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Alhaiti","sequence":"additional","affiliation":[{"name":"Department of Nursing, College of Applied Sciences, Almaarefa University, Diriyah, 13713, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebtesam Abdulrahman","family":"Jibreel","sequence":"additional","affiliation":[{"name":"Department of Nursing, College of Applied Sciences, Almaarefa University, Diriyah, 13713, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,12,29]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"crossref","unstructured":"Adewuya A. 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