{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T12:29:15Z","timestamp":1777811355801,"version":"3.51.4"},"reference-count":7,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2001,12,1]],"date-time":"2001-12-01T00:00:00Z","timestamp":1007164800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2001,12]]},"abstract":"<jats:p>\n                    The bone surrounding the teeth is constantly re-modeled throughout life, particularly during tooth movement and following tooth loss. Alveolar bone proper contains many highly oriented extrinsic fibers, but whether their orientation affects resorption is unknown. To determine if it does, we selected sperm whale cementum to provide large anisotropic substrates resembling extrinsic fiber bone. Slices cut either perpendicular or parallel to the extrinsic fiber axis were cultured for 24 hours with pre-hatched chick osteoclasts. Resorption pit areas and volumes were measured by video-rate reflection confocal microscopic mapping. Pits in the perpendicular group were smaller in area and were deeper than those in the parallel group (median values, 402 \u03bcm\n                    <jats:sup>2<\/jats:sup>\n                    and 572 \u03bcm\n                    <jats:sup>2<\/jats:sup>\n                    , n &gt; 950, p &lt; 0.0001; volume\/area 5.37 \u03bcm and 4.58 \u03bcm); volume differences only just reached significance (2137 \u03bcm\n                    <jats:sup>3<\/jats:sup>\n                    and 2554 \u03bcm\n                    <jats:sup>3<\/jats:sup>\n                    , p &lt; 0.05). These results show that the fiber orientation within a substrate can profoundly influence the shape of resorption lacunae. This pattern of resorption may help in the maintenance of an optimally functioning attachment of periodontal ligament fibers to alveolar bone.\n                  <\/jats:p>","DOI":"10.1177\/00220345010800121201","type":"journal-article","created":{"date-parts":[[2009,1,8]],"date-time":"2009-01-08T19:39:42Z","timestamp":1231443582000},"page":"2085-2088","source":"Crossref","is-referenced-by-count":5,"title":["Collagen Fiber Orientation Affects Osteoclastic Resorption"],"prefix":"10.1177","volume":"80","author":[{"given":"V.J.","family":"Kingsmill","sequence":"first","affiliation":[{"name":"Department of Adult Oral Health, Barts & the London Queen Mary's School of Medicine and Dentistry, Turner Street, London El 2AD, UK,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Boyde","sequence":"additional","affiliation":[{"name":"Department of Anatomy & Developmental Biology, University College London, Gower Street, London, WC1E 6BT, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2001,12,1]]},"reference":[{"key":"atypb1","unstructured":"Boyde A. (1971). Comparative histology of mammalian teeth. In: Dental morphology and evolution. Dahlberg AA, editor. Chicago: University of Chicago Press, pp. 81-94."},{"key":"atypb2","unstructured":"Boyde A. (1984). Methodology of calcified tissue specimen preparation for scanning electron microscopy. In: Methods of calcified tissue preparation. Dickson GR, editor. Amsterdam: Elsevier, pp. 251-308."},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4757-5348-6_15"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4805313"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1007\/BF00298589"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1007\/BF00824338"},{"key":"atypb7","first-page":"181","volume":"5","author":"Voegel JC","year":"1977","journal-title":"J Biol Buccale"}],"container-title":["Journal of Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00220345010800121201","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00220345010800121201","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:02:30Z","timestamp":1777496550000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00220345010800121201"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,12]]},"references-count":7,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2001,12]]}},"alternative-id":["10.1177\/00220345010800121201"],"URL":"https:\/\/doi.org\/10.1177\/00220345010800121201","relation":{},"ISSN":["0022-0345","1544-0591"],"issn-type":[{"value":"0022-0345","type":"print"},{"value":"1544-0591","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,12]]}}}