{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T12:37:30Z","timestamp":1777811850317,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2009,1,1]],"date-time":"2009-01-01T00:00:00Z","timestamp":1230768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2009,1]]},"abstract":"<jats:p>Oral manifestations of diseases caused by bioterrorist agents could be a potential data source for biosurveillance. This study had the objectives of determining the oral manifestations of diseases caused by bioterrorist agents, measuring the prevalence of these manifestations in emergency department reports, and constructing and evaluating a detection algorithm based on them. We developed a software application to detect oral manifestations in free text and identified positive reports over three years of data. The normal frequency in reports for oral manifestations related to anthrax (including buccal ulcers-sore throat) was 7.46%. The frequency for tularemia was 6.91%. For botulism and smallpox, the frequencies were 0.55% and 0.23%. We simulated outbreaks for these bioterrorism diseases and evaluated the performance of our system. The detection algorithm performed better for smallpox and botulism than for anthrax and tularemia. We found that oral manifestations can be a valuable tool for biosurveillance.<\/jats:p>","DOI":"10.1177\/0022034508327546","type":"journal-article","created":{"date-parts":[[2009,1,8]],"date-time":"2009-01-08T19:39:42Z","timestamp":1231443582000},"page":"89-94","source":"Crossref","is-referenced-by-count":6,"title":["Detection of Disease Outbreaks by the Use of Oral                Manifestations"],"prefix":"10.1177","volume":"88","author":[{"given":"M.H.","family":"Torres-Urquidy","sequence":"first","affiliation":[{"name":"Department of Biomedical Informatics, School of Medicine, University\r               of Pittsburgh, 3501 Terrace St., Suite 339, Pittsburgh, PA 15213, USA;"},{"name":"Center for Dental Informatics, School of Dental Medicine, University\r               of Pittsburgh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Wallstrom","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, School of Medicine, University\r               of Pittsburgh, 3501 Terrace St., Suite 339, Pittsburgh, PA 15213, USA;"},{"name":"Center for Dental Informatics, School of Dental Medicine, University\r               of Pittsburgh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.K.L.","family":"Schleyer","sequence":"additional","affiliation":[{"name":"Department of Biomedical Informatics, School of Medicine, University\r               of Pittsburgh, 3501 Terrace St., Suite 339, Pittsburgh, PA 15213, USA;"},{"name":"Center for Dental Informatics, School of Dental Medicine, University\r               of Pittsburgh"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2009,1,1]]},"reference":[{"key":"bibr-BUEHLER-ETAL-2004","unstructured":"Buehler JW, Hopkins RS, Overhage JM, Sosin DM, Tong V, CDC\n               Working Group (2004). Framework for evaluating public health\n               surveillance systems for early detection of outbreaks: recommendations from the CDC\n               Working Group. MMWR Recomm Rep53:1\u201311."},{"key":"bibr-CENTERS-FOR-DISEASE-CONTROL-AND-PREVENTION-2008","unstructured":"Centers for Disease Control and Prevention\n                  (2008). Syndromic surveillance: an applied approach to outbreak\n               detection. http:\/\/www.cdc.gov\/ncphi\/disss\/nndss\/syndromic.htm (accessed Sept 24,\n               2008)"},{"key":"bibr-CHAPMAN-ETAL-2001","doi-asserted-by":"publisher","DOI":"10.1006\/jbin.2001.1029"},{"key":"bibr-CHAPMAN-ETAL-2004A","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2004.03.002"},{"key":"bibr-CHAPMAN-ETAL-2004B","unstructured":"Chapman WW, Fiszman M, Dowling JN, Chapman BE, Rindflesch\n               TC (2004b). Identifying respiratory findings in emergency department\n               reports for biosurveillance using MetaMap. Stud Health Technol\n                  Inform107(Pt 1):487\u2013491."},{"key":"bibr-DUCHIN-2003","doi-asserted-by":"publisher","DOI":"10.1093\/jurban\/jtg115"},{"key":"bibr-FAWCETT-AND-PROVOST-1999","doi-asserted-by":"crossref","unstructured":"Fawcett T, Provost F (1999). Activity\n               monitoring: noticing interesting changes in behavior. Proceedings of the Fifth\n               International Conference on Knowledge Discovery and Data Mining. http:\/\/doi.acm.org\/10.1145\/312129.312195 (accessed\n               Sept 24, 2008)","DOI":"10.1145\/312129.312195"},{"key":"bibr-FLORES-ETAL-2003","doi-asserted-by":"publisher","DOI":"10.1016\/j.cden.2003.08.003"},{"key":"bibr-GOLDENBERG-ETAL-2002","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.042117499"},{"key":"bibr-GUPTA-ETAL-2004","doi-asserted-by":"publisher","DOI":"10.1309\/E6K33GBPE5C27FYU"},{"key":"bibr-JERNIGAN-ETAL-2001","doi-asserted-by":"publisher","DOI":"10.3201\/eid0706.010604"},{"key":"bibr-MELTZER-ETAL-2001","doi-asserted-by":"publisher","DOI":"10.3201\/eid0706.010607"},{"key":"bibr-PENNSYLVANIA-DEPARTMENT-HEALTH-2007","unstructured":"Pennsylvania Department of Health (2007).\n               Data from the Annual Hospital Questionnaire, Reporting Period July 1, 2001\u2014June 30,\n               2002. Pennsylvania Department of Health, Bureau of Health Statistics and Research.\n                  http:\/\/www.dsf.health.state.pa.us\/health\/lib\/health\/facilities\/hosamb\/2001-2002\/H0204.PDF.\n               (accessed Sept 24, 2008)"},{"key":"bibr-REIS-ETAL-2003","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0335026100"},{"key":"bibr-SAMARANAYAKE-AND-PEIRIS-2004","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2004.0405"},{"key":"bibr-WAGNER-2006","unstructured":"Wagner MM (2006). Introduction. In: Handbook\n               of biosurveillance. Wagner MM, Moore AW, Aryel RM, editors. Burlington: Elsevier\n               Academic Press, pp. 3\u201312."},{"key":"bibr-WAGNER-ETAL-2001A","doi-asserted-by":"publisher","DOI":"10.1097\/00124784-200107060-00006"},{"key":"bibr-WAGNER-ETAL-2001B","unstructured":"Wagner M, Aryel R, Dato VM, Krenzelok E, Fapohunda A,\n               Sharma R (2001b). Availability and comparative value of data elements\n               required for an effective detection system. Contract No. 290-00-0009. Rockville, MD:\n               Agency for Healthcare Research and Quality."},{"key":"bibr-WAGNER-ETAL-2003","doi-asserted-by":"publisher","DOI":"10.1016\/S1532-0464(03)00065-0"},{"key":"bibr-WALLSTROM-ETAL-2005","unstructured":"Wallstrom GL, Wagner M, Hogan W (2005).\n               High-fidelity injection detectability experiments: a tool for evaluating syndromic\n               surveillance systems. MMWR Morb Mortal Wkly Rep54(Suppl):85\u201391."},{"key":"bibr-WONG-AND-MOORE-2006","doi-asserted-by":"crossref","unstructured":"Wong WK, Moore AW (2006). Classical\n               time-series methods for biosurveillance. In: Handbook of biosurveillance. Wagner MM,\n               Moore AW, Aryel R, editors. Burlington: Academic Press, pp. 217\u2013234.","DOI":"10.1016\/B978-012369378-5\/50016-8"}],"container-title":["Journal of Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0022034508327546","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0022034508327546","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0022034508327546","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:04:34Z","timestamp":1777496674000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0022034508327546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009,1]]}},"alternative-id":["10.1177\/0022034508327546"],"URL":"https:\/\/doi.org\/10.1177\/0022034508327546","relation":{},"ISSN":["0022-0345","1544-0591"],"issn-type":[{"value":"0022-0345","type":"print"},{"value":"1544-0591","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,1]]}}}