{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:05:22Z","timestamp":1788307522109,"version":"build-2803163510"},"reference-count":35,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2010,1,28]],"date-time":"2010-01-28T00:00:00Z","timestamp":1264636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2010,3]]},"abstract":"<jats:p>\n                    Remineralization of demineralized dentin lesions adjacent to glass-ionomer cements (GICs) has been reported in the literature. This study tested the hypothesis that a strontium-based GIC can remineralize completely demineralized dentin by nucleation of new apatite crystallites within an apatite-free dentin matrix. Human dentin specimens were acid-etched, bonded with Fuji IX\n                    <jats:sub>GP<\/jats:sub>\n                    , and immersed in a calcium-and-phosphate-containing 1.5X simulated body fluid (SBF) for 1\u20134 months. Polyacrylic acid and polyvinylphosphonic acid biomimetic analogs were added to the SBFs to create 2 additional remineralization media. Specimens were processed by transmission electron microscopy (TEM). No apatite deposition could be identified in the completely demineralized dentin in any of the specimens immersed in the 3 remineralization media, despite TEM\/EDX evidence of diffusion of ions specific to the strontium-based GIC into the demineralized dentin. The hypothesis was rejected; mineral concentration alone is not a sufficient endpoint for assessing the success of contemporary remineralization strategies.\n                  <\/jats:p>","DOI":"10.1177\/0022034509357172","type":"journal-article","created":{"date-parts":[[2010,1,28]],"date-time":"2010-01-28T22:19:58Z","timestamp":1264717198000},"page":"230-235","source":"Crossref","is-referenced-by-count":69,"title":["Failure of a Glass Ionomer to Remineralize Apatite-depleted Dentin"],"prefix":"10.1177","volume":"89","author":[{"given":"Y.K.","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry, School of Dentistry, Kyungpook National University, Daegu, Korea;"},{"name":"Pediatric Dentistry & Orthodontics, Faculty of Dentistry, University of Hong Kong, Hong Kong SAR, China;"},{"name":"Department of Conservative Dentistry, School of Dentistry, KyungHee University, Seoul, Korea;"},{"name":"Department of Operative Dentistry and Endodontics, Guanghua School of Stomatology, Sun Yatsen University, Guangzhou, China;"},{"name":"Department of Endodontics, School of Dentistry, Medical College of Georgia, Augusta, GA 30912-1129, USA; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.K.Y.","family":"Yiu","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry, School of Dentistry, Kyungpook National University, Daegu, Korea;"},{"name":"Pediatric Dentistry & Orthodontics, Faculty of Dentistry, University of Hong Kong, Hong Kong SAR, China;"},{"name":"Department of Conservative Dentistry, School of Dentistry, KyungHee University, Seoul, Korea;"},{"name":"Department of Operative Dentistry and Endodontics, Guanghua School of Stomatology, Sun Yatsen University, Guangzhou, China;"},{"name":"Department of Endodontics, School of Dentistry, Medical College of Georgia, Augusta, GA 30912-1129, USA; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.R.","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry, School of Dentistry, Kyungpook National University, Daegu, Korea;"},{"name":"Pediatric Dentistry & Orthodontics, Faculty of Dentistry, University of Hong Kong, Hong Kong SAR, China;"},{"name":"Department of Conservative Dentistry, School of Dentistry, KyungHee University, Seoul, Korea;"},{"name":"Department of Operative Dentistry and Endodontics, Guanghua School of Stomatology, Sun Yatsen University, Guangzhou, China;"},{"name":"Department of Endodontics, School of Dentistry, Medical College of Georgia, Augusta, GA 30912-1129, USA; 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