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Cases were 190 Hong Kong Chinese patients with severe chronic periodontitis, and there were 169 periodontitis-free individuals as controls. Genotype CC and allele C of rs445509 ( p &lt; 0.0001, OR = 0.30) of FCGR3A were significantly more prevalent among control individuals than among cases, after adjustment for age, sex, and smoking. Smoking was significantly associated with chronic periodontitis ( p = 0.003, OR = 3.35). Within the limitations of this study, SNP rs445509 of FCGR3A seem to be negatively associated, while smoking was positively associated, with severe chronic periodontitis among Hong Kong Chinese.<\/jats:p>","DOI":"10.1177\/0022034510365444","type":"journal-article","created":{"date-parts":[[2010,5,3]],"date-time":"2010-05-03T22:48:24Z","timestamp":1272926904000},"page":"705-710","source":"Crossref","is-referenced-by-count":20,"title":["SNPs of Fc-gamma Receptor Genes and Chronic Periodontitis"],"prefix":"10.1177","volume":"89","author":[{"given":"L.","family":"Chai","sequence":"first","affiliation":[{"name":"Faculty of Dentistry, The University of Hong Kong, Prince Philip Dental Hospital, 34 Hospital Road, Hong Kong SAR, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.-Q.","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, 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