{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:04:37Z","timestamp":1790827477392,"version":"4.1.0"},"reference-count":38,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2010,6,18]],"date-time":"2010-06-18T00:00:00Z","timestamp":1276819200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2010,10]]},"abstract":"<jats:p>Root canal therapy (RCT) and tooth extraction are the main treatment options for irreversible pulpitis or its sequelae. Pulpotomy is an alternative treatment; however, more evidence is required. If outcomes of pulpotomy with a calcium-enriched mixture (PCEM) are non-inferior for mature molars with irreversible pulpitis compared with those from one-visit RCT (ORCT), this may be a beneficial treatment option. Four hundred seven individuals met the inclusion criteria and were randomly allocated [PCEM (n = 205), ORCT (n = 202)]. We used NRS questionnaires to record pain intensity. Six-month clinical and radiographic successes were assessed. Individuals in the ORCT arm reported significantly more post-operative pain than those in the PCEM arm (P &lt; 0.001). Clinical success rates in the two arms showed no statistically significant difference; however, the radiographic success rates were significantly greater in the PCEM arm (P &lt; 0.001). This trial suggests PCEM as an alternative for treatment of irreversible pulpitis. If long-term results confirm initial ones, PCEM may revolutionize oral health worldwide.<\/jats:p>","DOI":"10.1177\/0022034510374057","type":"journal-article","created":{"date-parts":[[2010,6,20]],"date-time":"2010-06-20T20:23:03Z","timestamp":1277065383000},"page":"1080-1085","source":"Crossref","is-referenced-by-count":17,"title":["A Clinical Trial of Pulpotomy\n                    <i>vs<\/i>\n                    . Root Canal Therapy of Mature Molars"],"prefix":"10.1177","volume":"89","author":[{"given":"S.","family":"Asgary","sequence":"first","affiliation":[{"name":"Iranian Center for Endodontic Research, Dental Research Center, Dental School, Shahid Beheshti University MC, Evin, Postal Code 1983963113, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.J.","family":"Eghbal","sequence":"additional","affiliation":[{"name":"Iranian Center for Endodontic Research, Dental Research Center, Dental School, Shahid Beheshti University MC, Evin, Postal Code 1983963113, Tehran, 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