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Dentin was exposed in premolars in 14 participants aged 15-25 years. Stimuli were applied to etched dentin immediately after cavity preparation and after the cavity had been filled with gutta percha for 7 days. This treatment increased significantly the intensity of pain produced by cold, and at the same time decreased that evoked by negative pressure stimuli. Pulpal blood flow was increased in the treated teeth, indicating that their pulps were inflamed. It is concluded that the sensory receptors responsible for the response to cold were probably sensitive to some change other than an outward flow of fluid in dentinal tubules, which would be caused by both forms of stimulus.<\/jats:p>","DOI":"10.1177\/0022034510395022","type":"journal-article","created":{"date-parts":[[2011,1,11]],"date-time":"2011-01-11T21:59:15Z","timestamp":1294783155000},"page":"678-682","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Sensory Transduction in Human Teeth with Inflamed Pulps"],"prefix":"10.1177","volume":"90","author":[{"given":"O.","family":"Ajcharanukul","sequence":"first","affiliation":[{"name":"Department of Stomatology, Faculty of Dentistry, Srinakharinwirot University, Bangkok 10500, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Chidchuangchai","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Charoenlarp","sequence":"additional","affiliation":[{"name":"Department of Physiology and Biochemistry, Faculty of Dentistry, Mahidol University, Yothi Street, Rajthavee, Bangkok 10400, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Vongsavan","sequence":"additional","affiliation":[{"name":"Department of Physiology and Biochemistry, Faculty of Dentistry, Mahidol University, Yothi Street, Rajthavee, Bangkok 10400, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Matthews","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pharmacology, School of Medical Sciences, University of Bristol, University Walk, Bristol BS8 1TD, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,1,11]]},"reference":[{"key":"bibr1-0022034510395022","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2006.12.015"},{"key":"bibr2-0022034510395022","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(67)90227-0"},{"key":"bibr3-0022034510395022","doi-asserted-by":"publisher","DOI":"10.1177\/00220345580370041401"},{"key":"bibr4-0022034510395022","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.2000.00791.x"},{"key":"bibr5-0022034510395022","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2002.022947"},{"key":"bibr6-0022034510395022","first-page":"73","volume-title":"Sensory mechanisms in dentine","author":"Br\u00e4nnstr\u00f6m M","year":"1963"},{"key":"bibr7-0022034510395022","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2006.12.014"},{"key":"bibr8-0022034510395022","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2006.09.009"},{"key":"bibr9-0022034510395022","first-page":"133","volume":"88","author":"Hirvonen T","year":"1992","journal-title":"Proc Finn Dent Soc"},{"key":"bibr10-0022034510395022","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1987.sp016520"},{"key":"bibr11-0022034510395022","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1997.tb01194.x"},{"key":"bibr12-0022034510395022","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1954.0199"},{"key":"bibr13-0022034510395022","doi-asserted-by":"publisher","DOI":"10.3109\/00016357909004706"},{"key":"bibr14-0022034510395022","doi-asserted-by":"publisher","DOI":"10.1002\/jez.b.21264"},{"key":"bibr15-0022034510395022","first-page":"183","volume":"26","author":"Massler M","year":"1956","journal-title":"NY J Dent"},{"key":"bibr16-0022034510395022","first-page":"80","volume-title":"Sensory mechanisms in dentine","author":"Naylor MN","year":"1963"},{"key":"bibr17-0022034510395022","doi-asserted-by":"publisher","DOI":"10.12968\/denu.2001.28.4.200"},{"key":"bibr18-0022034510395022","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0011-8532(22)01128-4","volume":"34","author":"Pashley DH","year":"1990","journal-title":"Dent Clin North Am"},{"key":"bibr19-0022034510395022","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(84)90179-1"},{"key":"bibr20-0022034510395022","doi-asserted-by":"publisher","DOI":"10.1177\/10454411000110010401"},{"key":"bibr21-0022034510395022","doi-asserted-by":"publisher","DOI":"10.1177\/0022034509343413"},{"key":"bibr22-0022034510395022","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9969(03)00011-6"},{"key":"bibr23-0022034510395022","unstructured":"Veerayutthwilai O (2001). 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