{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T05:04:25Z","timestamp":1790139865429,"version":"4.0.1"},"reference-count":55,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2012,4,23]],"date-time":"2012-04-23T00:00:00Z","timestamp":1335139200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p>We propose a new classification of severe early childhood caries (S-ECC): hypoplasia-associated severe early childhood caries (HAS-ECC). This form of caries affects mostly young children living at or below poverty, characterized by structurally damaged primary teeth that are particularly vulnerable to dental caries. These predisposing developmental dental defects are mainly permutations of enamel hypoplasia (EHP). Anthropologists and dental researchers consider EHP an indicator for infant and maternal stresses including malnutrition, a variety of illnesses, and adverse birthing conditions. Differentiation of HAS-ECC from other forms of early childhood caries is warranted because of its distinct etiology, clinical presentation, and eventual management. Defining HAS-ECC has important clinical implications: Therapies that control or prevent other types of caries are likely to be less effective with HAS-ECC because the structural integrity of the teeth is compromised prior to their emergence into the oral cavity. By the time these children present to the dentist, the treatment options often become limited to surgical management under general anesthesia. To prevent HAS-ECC, dentists must partner with other health providers to develop interventions that begin with pregnant mothers, with the aim of eliminating or ameliorating the covariates accompanying poverty, including better pre- and post-natal care and nutrition.<\/jats:p>","DOI":"10.1177\/0022034512444929","type":"journal-article","created":{"date-parts":[[2012,4,24]],"date-time":"2012-04-24T00:46:36Z","timestamp":1335228396000},"page":"544-550","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":133,"title":["Hypoplasia-associated Severe Early Childhood Caries \u2013 A Proposed Definition"],"prefix":"10.1177","volume":"91","author":[{"given":"P.W.","family":"Caufield","sequence":"first","affiliation":[{"name":"Cariology and Comprehensive, New York University College of Dentistry, New York, NY 10010, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Li","sequence":"additional","affiliation":[{"name":"Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, NY 10010, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.G.","family":"Bromage","sequence":"additional","affiliation":[{"name":"Biomaterials and Biomimetics, New York University College of Dentistry, New York, NY 10010, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2012,4,23]]},"reference":[{"key":"bibr1-0022034512444929","doi-asserted-by":"publisher","DOI":"10.1002\/ajpa.21258"},{"key":"bibr2-0022034512444929","doi-asserted-by":"publisher","DOI":"10.1177\/00220345930720120701"},{"key":"bibr3-0022034512444929","unstructured":"American Academy of Pediatric Dentistry (2011). 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