{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T10:25:12Z","timestamp":1780482312652,"version":"3.54.1"},"reference-count":24,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2012,4,20]],"date-time":"2012-04-20T00:00:00Z","timestamp":1334880000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2012,6]]},"abstract":"<jats:p>\n                    Central nervous system organization of masticatory muscles determines the magnitude of joint and muscle forces. Validated computer-assisted models of neuromuscular organization during biting were used to determine organization in individuals with and without temporomandibular disorders (TMD). Ninety-one individuals (47 women, 44 men) were assigned to one of four diagnostic groups based on the presence (+) or absence (-) of pain (P) and bilateral temporomandibular joint disc displacement (DD). Electromyography and bite-forces were measured during right and left incisor and molar biting. Two three-dimensional models employing neuromuscular objectives of minimization of joint loads (MJL) or muscle effort (MME) simulated biting tasks. Evaluations of diagnostic group and gender effects on choice of best-fit model were by analysis of variance (ANOVA) and Tukey-Kramer post hoc tests, evaluations of right-left symmetry were by Chi-square and Fisher\u2019s exact statistics, and evaluations of model accuracy were by within-subject linear regressions. MME was the best-fit during left molar biting in +DD individuals and incisor biting in men (all p &lt; 0.03). Incisor biting symmetry in muscle organization was significantly higher (p &lt; 0.03) in healthy individuals compared with those with TMD. Within-subject regressions showed that best-fit model errors were similar among groups: 8 to 15% (0.68 \u2264 R\n                    <jats:sup>2<\/jats:sup>\n                    \u2264 0.74). These computer-assisted models predicted muscle organization during static biting in humans with and without TMDs.\n                  <\/jats:p>","DOI":"10.1177\/0022034512445909","type":"journal-article","created":{"date-parts":[[2012,4,21]],"date-time":"2012-04-21T04:10:27Z","timestamp":1334981427000},"page":"568-573","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":24,"title":["Muscle Organization in Individuals with and without Pain and Joint Dysfunction"],"prefix":"10.1177","volume":"91","author":[{"given":"J.C.","family":"Nickel","sequence":"first","affiliation":[{"name":"University of Missouri-Kansas City, School of Dentistry, Departments of Orthodontics & Dentofacial Orthopedics and Oral Biology, 650 East 25th St., Kansas City, MO 64108, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.M.","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"University at Buffalo, School of Dental Medicine, Department of Oral Diagnostic Sciences, Buffalo, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.D.","family":"McCall","sequence":"additional","affiliation":[{"name":"University at Buffalo, School of Dental Medicine, Department of Oral Diagnostic Sciences, Buffalo, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Ohrbach","sequence":"additional","affiliation":[{"name":"University at Buffalo, School of Dental Medicine, Department of Oral Diagnostic Sciences, Buffalo, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.B.","family":"Marx","sequence":"additional","affiliation":[{"name":"University of Nebraska-Lincoln, Department of Statistics, 340 Hardin Hall North, Lincoln, NE, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Liu","sequence":"additional","affiliation":[{"name":"University of Missouri-Kansas City, School of Dentistry, Departments of Orthodontics & Dentofacial Orthopedics and Oral Biology, 650 East 25th St., Kansas City, MO 64108, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.R.","family":"Iwasaki","sequence":"additional","affiliation":[{"name":"University of Missouri-Kansas City, School of Dentistry, Departments of Orthodontics & Dentofacial Orthopedics and Oral Biology, 650 East 25th St., Kansas City, MO 64108, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2012,4,20]]},"reference":[{"key":"bibr1-0022034512445909","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2009.02.023"},{"key":"bibr2-0022034512445909","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.1985.tb01292.x"},{"key":"bibr3-0022034512445909","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2009.02.027"},{"key":"bibr4-0022034512445909","first-page":"301","volume":"6","author":"Dworkin SF","year":"1992","journal-title":"J Craniomandib Disord"},{"key":"bibr5-0022034512445909","doi-asserted-by":"publisher","DOI":"10.5014\/ajot.42.6.378"},{"key":"bibr6-0022034512445909","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0722.2011.00823.x"},{"key":"bibr7-0022034512445909","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2010.02149.x"},{"key":"bibr8-0022034512445909","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-5406(03)00575-4"},{"key":"bibr9-0022034512445909","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-9969(03)00171-7"},{"key":"bibr10-0022034512445909","first-page":"235","volume":"18","author":"Iwasaki LR","year":"2004","journal-title":"J Orofac Pain"},{"key":"bibr11-0022034512445909","doi-asserted-by":"publisher","DOI":"10.4081\/or.2009.e29"},{"key":"bibr12-0022034512445909","first-page":"405","volume-title":"Temporomandibular disorders and orofacial pain - 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