{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T19:28:52Z","timestamp":1792524532507,"version":"4.5.0"},"reference-count":30,"publisher":"SAGE Publications","issue":"7_suppl","license":[{"start":{"date-parts":[[2013,5,20]],"date-time":"2013-05-20T00:00:00Z","timestamp":1369008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:p>The authors tested the hypothesis that obstructive sleep apnea (OSA) signs\/symptoms are associated with the occurrence of temporomandibular disorder (TMD), using the OPPERA prospective cohort study of adults aged 18 to 44 years at enrollment (n = 2,604) and the OPPERA case-control study of chronic TMD (n = 1,716). In both the OPPERA cohort and case-control studies, TMD was examiner determined according to established research diagnostic criteria. People were considered to have high likelihood of OSA if they reported a history of sleep apnea or \u2265 2 hallmarks of OSA: loud snoring, daytime sleepiness, witnessed apnea, and hypertension. Cox proportional hazards regression estimated hazard ratios (HRs) and 95% confidence limits (CL) for first-onset TMD. Logistic regression estimated odds ratios (OR) and 95% CL for chronic TMD. In the cohort, 248 individuals developed first-onset TMD during the median 2.8-year follow-up. High likelihood of OSA was associated with greater incidence of first-onset TMD (adjusted HR = 1.73; 95% CL, 1.14, 2.62). In the case-control study, high likelihood of OSA was associated with higher odds of chronic TMD (adjusted OR = 3.63; 95% CL, 2.03, 6.52). Both studies supported a significant association of OSA symptoms and TMD, with prospective cohort evidence finding that OSA symptoms preceded first-onset TMD.<\/jats:p>","DOI":"10.1177\/0022034513488140","type":"journal-article","created":{"date-parts":[[2013,5,21]],"date-time":"2013-05-21T00:57:07Z","timestamp":1369097827000},"page":"S70-S77","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":136,"title":["Sleep Apnea Symptoms and Risk of Temporomandibular Disorder"],"prefix":"10.1177","volume":"92","author":[{"given":"A.E.","family":"Sanders","sequence":"first","affiliation":[{"name":"University of North Carolina at Chapel Hill, Koury Oral Health Sciences Building, 385 South Columbia Street, Chapel Hill, NC 27599-7450, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.K.","family":"Essick","sequence":"additional","affiliation":[{"name":"University of North Carolina at Chapel Hill, Koury Oral 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at Chapel Hill, Koury Oral Health Sciences Building, 385 South Columbia Street, Chapel Hill, NC 27599-7450, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Maixner","sequence":"additional","affiliation":[{"name":"University of North Carolina at Chapel Hill, Koury Oral Health Sciences Building, 385 South Columbia Street, Chapel Hill, NC 27599-7450, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Dubner","sequence":"additional","affiliation":[{"name":"University of Maryland, Baltimore, MD, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Bair","sequence":"additional","affiliation":[{"name":"University of North Carolina at Chapel Hill, Koury Oral Health Sciences Building, 385 South Columbia Street, Chapel Hill, NC 27599-7450, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.E.","family":"Miller","sequence":"additional","affiliation":[{"name":"School of Global 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