{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:24:19Z","timestamp":1787066659400,"version":"build-2736575974"},"reference-count":20,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2013,10,15]],"date-time":"2013-10-15T00:00:00Z","timestamp":1381795200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:p>Biodegradable osteosynthesis could reduce\/delete the problems associated with titanium plate removal. The aim of the present study was to compare the clinical performance in the first 2 post-operative years between a biodegradable and a titanium system in oral and maxillofacial surgery. The multicenter randomized controlled trial (RCT) was performed in the Netherlands from December 2006 to July 2009. Included were 230 patients who underwent a bilateral sagittal split osteotomy (BSSO) and\/or a Le Fort-I osteotomy and those treated for fractures of the mandible, maxilla, or zygoma. The patients were randomly assigned to a titanium group (KLS Martin) or to a biodegradable group (Inion CPS). Plate removal was necessary in 16 of the 134 patients (11.9%) treated with titanium and in 21 of the 87 patients (24.1%) treated with the biodegradable system within the first 2 post-operative years [ p = .016, HR biodegradable (95% CI) = 2.2 (1.1-4.2), HR titanium = 1]. Occlusion, VAS, and MFIQ scores showed that both groups had good mandibular function and were (almost) free of pain 1 and 2 years post-operatively ( http:\/\/controlled-trials.com ISRCTN 44212338).<\/jats:p>","DOI":"10.1177\/0022034513508953","type":"journal-article","created":{"date-parts":[[2013,10,16]],"date-time":"2013-10-16T00:45:22Z","timestamp":1381884322000},"page":"1100-1105","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":47,"title":["Comparison of Biodegradable and Titanium Fixation Systems in Maxillofacial Surgery"],"prefix":"10.1177","volume":"92","author":[{"given":"N.B.","family":"van Bakelen","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, University Medical Centre Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.J.","family":"Buijs","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, University Medical Centre Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Jansma","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, University Medical Centre Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.G.A.M.","family":"de Visscher","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Medical Centre Leeuwarden, P.O. Box 888, 8901 BR Leeuwarden, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Th.J.M.","family":"Hoppenreijs","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Rijnstate Hospital Arnhem, 6800 TA Arnhem, P.O. Box 9555, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.E.","family":"Bergsma","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Amphia Hospital Breda, Postbus 90.158, 4800 RK Breda, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Stegenga","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, University Medical Centre Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands"},{"name":"UMCG Centre for Dentistry and Oral Hygiene, Department of Oral Health Care & Clinical Epidemiology, University Medical Centre Groningen, University of Groningen, P.O. Box 30.001, 9700 RB Groningen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.R.M.","family":"Bos","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, University Medical Centre Groningen, University of Groningen, P.O. 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Decision-making considerations in application of biodegradable fixation systems in maxillofacial surgery \u2013 a retrospective cohort study. J Craniomaxillofac Surg [Epub ahead of print 7\/5\/2013] (in press). 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