{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T12:45:05Z","timestamp":1793018705704,"version":"4.5.0"},"reference-count":26,"publisher":"SAGE Publications","issue":"12_suppl","license":[{"start":{"date-parts":[[2013,10,24]],"date-time":"2013-10-24T00:00:00Z","timestamp":1382572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2013,12]]},"abstract":"<jats:p>This review aimed at evaluating the effectiveness of reconstructive procedures for treating peri-implantitis. Searches of electronic databases and cross-referencing were performed for human comparative clinical trials with \u226510 implants for \u226512 months of follow-up, reporting radiographic defect fill and at least one of the following parameters: probing depth reduction, clinical attachment level gain, bleeding on probing reduction, and mucosal recession. The searches retrieved 430 citations. Only 1 randomized controlled trial was identified, which compared reconstructive therapy and open flap debridement. Case series studies were also included to evaluate the overall performance of the reconstructive procedures. Twelve studies were finally included. Meta-analysis revealed that the weighted mean radiographic defect fill was 2.17 mm (95% confidence interval [CI]: 1.46-2.87 mm), probing depth reduction was 2.97 mm (95% CI: 2.38-3.56 mm), clinical attachment level gain was 1.65 mm (95% CI: 1.17-2.13 mm), and bleeding on probing reduction was 45.8% (95% CI: 38.5%-53.3%). Great variability in reparative outcomes was found, attributed to patient factors, defect morphology, and reconstructive agents used. Currently, there is a lack of evidence for supporting additional benefit of reconstructive procedures to the other treatment modalities for managing peri-implantitis.<\/jats:p>","DOI":"10.1177\/0022034513509279","type":"journal-article","created":{"date-parts":[[2013,10,25]],"date-time":"2013-10-25T04:01:41Z","timestamp":1382673701000},"page":"131S-138S","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":66,"title":["Reconstructive Procedures for Treating Peri-implantitis"],"prefix":"10.1177","volume":"92","author":[{"given":"V.","family":"Khoshkam","sequence":"first","affiliation":[{"name":"Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HL.","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GH.","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.P.","family":"MacEachern","sequence":"additional","affiliation":[{"name":"Taubman Health Sciences Library, University of Michigan, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Monje","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Suarez","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.V.","family":"Giannobile","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"HL.","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2013,10,24]]},"reference":[{"key":"bibr1-0022034513509279","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2012.01880.x"},{"key":"bibr2-0022034513509279","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12013"},{"key":"bibr3-0022034513509279","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8208.2011.00387.x"},{"key":"bibr4-0022034513509279","first-page":"79","volume":"22","author":"Deppe H","year":"2007","journal-title":"Int J Oral Maxillofac Implants"},{"key":"bibr5-0022034513509279","first-page":"CD004970","volume":"1","author":"Esposito M","year":"2012","journal-title":"Cochrane Database Syst Rev"},{"key":"bibr6-0022034513509279","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2009.01375.x"},{"key":"bibr7-0022034513509279","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2010.01537.x"},{"key":"bibr8-0022034513509279","first-page":"11","volume":"32","author":"Froum SJ","year":"2012","journal-title":"Int J Periodontics Restorative Dent"},{"key":"bibr9-0022034513509279","unstructured":"Higgins JP, Green S (2011). 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