{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T12:41:39Z","timestamp":1777812099496,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2015,4,9]],"date-time":"2015-04-09T00:00:00Z","timestamp":1428537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:p>Numerous diseases are known to cause microstructural alteration of dental tissues structure. One type in particular is associated with neonatal jaundice and circulation of bilirubin in blood at high concentration due to increased hemolysis in conditions such as erythroblastosis fetalis, septicemia, biliary atresia, and other causes of hyperbilirubinemia. In those conditions, the products of the catabolism of hemoglobin end up deposited in various tissues, including teeth, where they can present clinically as visibly stained brown\/green teeth. There is almost no information on the nature or extent of the structural changes taking place in these conditions. Here, advanced nondestructive wide-angle synchrotron X-ray scattering techniques combined with scanning microscopy methods were used to investigate for the first time the ultrastructure of the dental hard tissues in an archival case of intrinsically pigmented green teeth. Despite no obvious elemental variation across the pigmented tissue region, the high-resolution crystallographic properties probed by wide-angle synchrotron X-ray scattering revealed an ultrastructural variation (orientation, particle size, and lattice parameter of hydroxyapatite crystallites) associated with a pigmentation line in dentine and with a distinct neonatal line in enamel.<\/jats:p>","DOI":"10.1177\/0022034515580987","type":"journal-article","created":{"date-parts":[[2015,4,9]],"date-time":"2015-04-09T22:12:22Z","timestamp":1428617542000},"page":"1004-1010","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["X-ray Study of Human Dental Tissues Affected by Erythroblastosis Fetalis"],"prefix":"10.1177","volume":"94","author":[{"given":"T.","family":"Sui","sequence":"first","affiliation":[{"name":"Multi-Beam Laboratory for Engineering Microscopy, Department of Engineering Science, University of Oxford, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Ying","sequence":"additional","affiliation":[{"name":"Multi-Beam Laboratory for Engineering Microscopy, Department of Engineering Science, University of Oxford, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.M.","family":"Korsunsky","sequence":"additional","affiliation":[{"name":"Multi-Beam Laboratory for Engineering Microscopy, Department of Engineering Science, University of Oxford, Oxford, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Landini","sequence":"additional","affiliation":[{"name":"School of Dentistry, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,4,9]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-4505.2008.00048.x"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2818.2001.00831.x"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1956.tb05435.x"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.2350\/10-10-0929-LET.1"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsb.2014.02.006"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2013.06.018"},{"issue":"3","key":"e_1_3_2_8_1","first-page":"220","article-title":"Effect of the birth process on the neonatal line in primary tooth enamel","volume":"11","author":"Eli I","year":"1989","unstructured":"Eli I, Sarnat H, Talmi E. 1989. Effect of the birth process on the neonatal line in primary tooth enamel. Pediatr Dent. 11(3):220\u2013223.","journal-title":"Pediatr Dent"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1136\/adc.30.151.224"},{"key":"e_1_3_2_10_1","unstructured":"Hammersley AP. 1997. FIT2D: an introduction and overview [accessed 2015 Mar 18]. http:\/\/www.esrf.eu\/computing\/scientific\/FIT2D\/FIT2D_INTRO\/fit2d.html."},{"key":"e_1_3_2_11_1","first-page":"148","article-title":"Anomalous jaundice, with enlargement of liver and spleen, and bile-stained teeth","volume":"5","author":"Langmead F","year":"1912","unstructured":"Langmead F. 1912. Anomalous jaundice, with enlargement of liver and spleen, and bile-stained teeth. Proc R Soc Med. 5(Sect Study Dis Child):148\u2013149.","journal-title":"Proc R Soc Med"},{"issue":"12","key":"e_1_3_2_12_1","first-page":"305","article-title":"Intrinsic staining of teeth following icterus gravis","volume":"44","author":"Marsland EA","year":"1953","unstructured":"Marsland EA, Gerrard JW. 1953. Intrinsic staining of teeth following icterus gravis. Br Dent J. 44(12):305\u2013310.","journal-title":"Br Dent J"},{"issue":"10","key":"e_1_3_2_13_1","first-page":"978","article-title":"The Scherrer formula for X-ray particle size determination","volume":"56","author":"Patterson A","year":"1939","unstructured":"Patterson A. 1939. The Scherrer formula for X-ray particle size determination. Phys Rev E Stat Nonlin Soft Matter Phys. 56(10):978\u2013982.","journal-title":"Phys Rev E Stat Nonlin Soft Matter Phys"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsb.2006.03.008"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2013.09.043"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2013.04.020"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2013.0928"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMicm1110461"},{"key":"e_1_3_2_19_1","first-page":"147","article-title":"Green teeth, subsequent to a prolonged jaundice in the first weeks of life","volume":"5","author":"Thursfield H","year":"1912","unstructured":"Thursfield H. 1912. Green teeth, subsequent to a prolonged jaundice in the first weeks of life. Proc R Soc Med. 5(Sect Study Dis Child):147\u2013148.","journal-title":"Proc R Soc Med"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0001-6160(53)90006-6"}],"container-title":["Journal of Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0022034515580987","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0022034515580987","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0022034515580987","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:05:41Z","timestamp":1777496741000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0022034515580987"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,9]]},"references-count":19,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2015,7]]}},"alternative-id":["10.1177\/0022034515580987"],"URL":"https:\/\/doi.org\/10.1177\/0022034515580987","relation":{},"ISSN":["0022-0345","1544-0591"],"issn-type":[{"value":"0022-0345","type":"print"},{"value":"1544-0591","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,9]]}}}