{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T01:36:38Z","timestamp":1788053798356,"version":"build-2784847793"},"reference-count":42,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2015,8,26]],"date-time":"2015-08-26T00:00:00Z","timestamp":1440547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:p>Modification to the dental occlusion may alter oral sensorimotor functions. Restorative treatments aim to restore sensorimotor functions; however, it is unclear why some patients fail to adapt to the restoration and remain with sensorimotor complaints. The face primary motor cortex (face-M1) is involved in the generation and control of orofacial movements. Altered sensory inputs or motor function can induce face-M1 neuroplasticity. We took advantage of the continuous eruption of the incisors in Sprague-Dawley rats and used intracortical microstimulation (ICMS) to map the jaw and tongue motor representations in face-M1. Specifically, we tested the hypothesis that multiple trimming of the right mandibular incisor, to keep it out of occlusal contacts for 7 d, and subsequent incisor eruption and restoration of occlusal contacts, can alter the ICMS-defined features of jaw and tongue motor representations (i.e., neuroplasticity). On days 1, 3, 5, and 7, the trim and trim-recovered groups had 1 to 2 mm of incisal trimming of the incisor; a sham trim group had buccal surface trimming with no occlusal changes; and a naive group had no treatment. Systematic mapping was performed on day 8 in the naive, trim, and sham trim groups and on day 14 in the trim-recovered group. In the trim group, the tongue onset latency was shorter in the left face-M1 than in the right face-M1 ( P &lt; .001). In the trim-recovered group, the number of tongue sites and jaw\/tongue overlapping sites was greater in the left face-M1 than in the right face-M1 ( P = 0.0032, 0.0016, respectively), and the center of gravity was deeper in the left than in the right face-M1 ( P = 0.026). Therefore, incisor trimming and subsequent restoration of occlusal contacts induced face-M1 neuroplasticity, reflected in significant disparities between the left and right face-M1 in some ICMS-defined features of the tongue motor representations. Such neuroplasticity may reflect or contribute to subjects\u2019 ability to adapt their oral sensorimotor functions to an altered dental occlusion.<\/jats:p>","DOI":"10.1177\/0022034515602478","type":"journal-article","created":{"date-parts":[[2015,8,26]],"date-time":"2015-08-26T22:39:42Z","timestamp":1440628782000},"page":"1757-1764","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":37,"title":["Dental Occlusal Changes Induce Motor Cortex Neuroplasticity"],"prefix":"10.1177","volume":"94","author":[{"given":"L.","family":"Avivi-Arber","sequence":"first","affiliation":[{"name":"Department of Oral Physiology, Faculty of Dentistry, University of Toronto, Toronto, Canada"},{"name":"Department of Prosthodontics, Faculty of Dentistry, University of Toronto, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.-C.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Oral Physiology, Faculty of Dentistry, University of Toronto, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.J.","family":"Sessle","sequence":"additional","affiliation":[{"name":"Department of Oral Physiology, Faculty of Dentistry, University of Toronto, Toronto, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,8,26]]},"reference":[{"key":"bibr1-0022034515602478","doi-asserted-by":"publisher","DOI":"10.1097\/00004691-200208000-00005"},{"key":"bibr2-0022034515602478","doi-asserted-by":"publisher","DOI":"10.1080\/08990220701470451"},{"key":"bibr3-0022034515602478","doi-asserted-by":"publisher","DOI":"10.1152\/jn.90609.2008"},{"key":"bibr4-0022034515602478","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4367-13.2014"},{"key":"bibr5-0022034515602478","unstructured":"Asanuma H. 1989. 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