{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T16:56:16Z","timestamp":1789750576059,"version":"4.0.1"},"reference-count":35,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T00:00:00Z","timestamp":1554336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2019,6]]},"abstract":"<jats:p>\n                    Patients with muscular temporomandibular disorder (TMD) present with abnormal oxygenation of the jaw muscles. Nonetheless, the deoxygenation pattern of jaw muscles of healthy subjects with frequent wake-time tooth-clenching episodes, who are at greater risk for TMD, has never been investigated. This case-control study compared the deoxygenation of the masseter during standardized tasks between TMD-free individuals with frequent self-reports of wake-time clenching and those with infrequent self-reports. University students ( N = 255) filled out the Oral Behavior Checklist. Fourteen females with high versus low scores\u2014high parafunctional (HP) group ( n = 7, \u226580th percentile of score distribution) versus low parafunctional (LP) group ( n = 7, \u226420th percentile)\u2014completed 2 sessions during which they clenched at their maximum voluntary contraction (MVC) for 2 min and at 10% to 20% MVC for 20 min. Tissue oxygen saturation (StO\n                    <jats:sub>2<\/jats:sub>\n                    ) and changes in oxygenated hemoglobin, deoxygenated hemoglobin, and total hemoglobin of the masseter were measured via near-infrared spectroscopy and analyzed with a generalized mixed effect model. A significant interaction effect (task \u00d7 study group) was found on all outcome measures, indicating that the deoxygenation pattern of the HP group differed from the LP group (all P &lt; 0.001). MVC of the masseter induced an almost 5-times-greater reduction of StO\n                    <jats:sub>2<\/jats:sub>\n                    in the HP group as compared with the LP group ( P = 0.023). However, the relative increase in StO\n                    <jats:sub>2<\/jats:sub>\n                    at rest after the MVC was similar between groups ( P &gt; 0.05). At the end of the prolonged MVC task (10% to 20%), the blood flow (change in total hemoglobin) was almost 6 times higher in the LP group as compared with baseline. On the contrary, it increased minimally in the HP group (all P &lt; 0.001). Healthy individuals at risk for TMD have abnormalities in masseter deoxygenation. Future prospective studies are needed to test whether this contributes to the onset of muscular TMD.\n                  <\/jats:p>","DOI":"10.1177\/0022034519837249","type":"journal-article","created":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T16:17:51Z","timestamp":1554394671000},"page":"666-672","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Masseter Deoxygenation in Adults at Risk for Temporomandibular Disorders"],"prefix":"10.1177","volume":"98","author":[{"given":"N.","family":"Shah","sequence":"first","affiliation":[{"name":"Faculty of Medicine, McMaster University, Hamilton, ON, Canada"},{"name":"Center for the Study of Pain, Faculty of Dentistry, University of Toronto, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3072-1576","authenticated-orcid":false,"given":"L.","family":"Melo","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, University of Toronto, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9980-8699","authenticated-orcid":false,"given":"W.D.","family":"Reid","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, University of Toronto, Toronto, ON, Canada"},{"name":"Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada"},{"name":"KITE, Toronto Rehab-University Health Network, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Cioffi","sequence":"additional","affiliation":[{"name":"Center for the Study of Pain, Faculty of Dentistry, University of Toronto, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,4,4]]},"reference":[{"key":"bibr1-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1111\/joor.12346"},{"key":"bibr2-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelekin.2015.04.006"},{"key":"bibr3-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0838.2001.110404.x"},{"key":"bibr4-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2005.01442.x"},{"key":"bibr5-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-018-2600-1"},{"key":"bibr6-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-016-1870-8"},{"key":"bibr7-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1186\/s40510-014-0027-z"},{"key":"bibr8-0022034519837249","doi-asserted-by":"publisher","DOI":"10.11607\/ofph.1960"},{"key":"bibr9-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2005.08.005"},{"key":"bibr10-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(96)00009-X"},{"key":"bibr11-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1111\/joor.12448"},{"key":"bibr12-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1177\/0022034510365448"},{"key":"bibr13-0022034519837249","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2011.0088"},{"key":"bibr14-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-7916(96)00027-4"},{"key":"bibr15-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1177\/154405910208100412"},{"key":"bibr16-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1007\/s004210050405"},{"key":"bibr17-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1097\/AJP.0b013e318270fa59"},{"issue":"4","key":"bibr18-0022034519837249","first-page":"306","volume":"20","author":"Markiewicz MR","year":"2006","journal-title":"J Orofac Pain"},{"key":"bibr19-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2009.02033.x"},{"issue":"3","key":"bibr20-0022034519837249","first-page":"168","volume":"26","author":"Michelotti A","year":"2012","journal-title":"J Orofac Pain"},{"key":"bibr21-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2013.07.018"},{"key":"bibr22-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(89)90189-9"},{"key":"bibr23-0022034519837249","doi-asserted-by":"publisher","DOI":"10.3109\/00016357.2014.954267"},{"key":"bibr24-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1259\/dmfr.20170052"},{"key":"bibr25-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2842.2003.01139.x"},{"issue":"1","key":"bibr26-0022034519837249","first-page":"6","volume-title":"J Oral Facial Pain Headache","volume":"28","author":"Schiffman E","year":"2014"},{"key":"bibr27-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultrasmedbio.2008.05.009"},{"key":"bibr28-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1111\/joor.12096"},{"key":"bibr29-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1177\/0022034516653743"},{"key":"bibr30-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1111\/joor.12450"},{"key":"bibr31-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-006-0497-4"},{"key":"bibr32-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-7916(02)00004-6"},{"key":"bibr33-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1117\/12.502380"},{"key":"bibr34-0022034519837249","doi-asserted-by":"publisher","DOI":"10.1007\/BF02015307"},{"key":"bibr35-0022034519837249","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2017.00689"}],"container-title":["Journal of Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0022034519837249","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0022034519837249","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0022034519837249","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:08:05Z","timestamp":1777496885000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0022034519837249"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,4]]},"references-count":35,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["10.1177\/0022034519837249"],"URL":"https:\/\/doi.org\/10.1177\/0022034519837249","relation":{},"ISSN":["0022-0345","1544-0591"],"issn-type":[{"value":"0022-0345","type":"print"},{"value":"1544-0591","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,4]]}}}