{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T09:38:33Z","timestamp":1793093913121,"version":"4.5.0"},"reference-count":43,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T00:00:00Z","timestamp":1770768000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82101026"],"award-info":[{"award-number":["82101026"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82370962"],"award-info":[{"award-number":["82370962"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:p>\n                    Given the limited effectiveness of Alzheimer\u2019s disease (AD) treatments, modifiable risk factors warrant attention. Oral pain (OP), a common inflammatory symptom, may be linked to neurodegeneration. This study aimed to investigate associations between OP and AD risk, cognitive performance, and brain structure. Data from 490,035 UK Biobank participants free of AD at baseline and with complete OP records were analyzed, while other dementias were excluded. Participants were categorized into an OP group (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u200933,697; defined as self-reported toothache or painful gums via touchscreen questionnaire) and an oral pain-free group (\n                    <jats:italic toggle=\"yes\">n<\/jats:italic>\n                    \u2009=\u2009456,338). AD diagnoses were ascertained using ICD-10 codes from linked electronic health records and analyzed in a cohort design using multivariable Cox proportional hazards models. A cross-sectional analysis method of cognitive and brain outcomes was performed using multivariable generalized linear models. Over an average follow-up period of 14.1\u2009\u00b1\u20091.7\u2009y, OP was associated with a 30.7% increased risk of AD (hazard ratio [HR]\u2009=\u20091.307, 95% confidence interval [CI]: 1.165 to 1.466,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u20090.001). Individuals with OP also demonstrated poorer cognitive functions and reduced gray matter volumes in the left parahippocampal gyrus (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    <jats:sub>adj<\/jats:sub>\n                    \u2009=\u20090.014, \u03b2\u2009=\u2009\u221227.383, SE\u2009=\u20097.728). Among those whose oral pain resolved, the occurrence of AD was lower (HR\u2009=\u20090.360, 95% CI: 0.197 to 0.660,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009=\u20090.011), along with improved cognitive functions and brain structures as compared with those with persistent OP. Proteomic analyses identified potential mediators, including GDF15, BCAN, and PLAUR, which are involved in pathways related to wound healing and immune regulation. Emerging evidence suggested a possible association between OP and AD through neuroimmune pathways, including potential Tau-related changes in the hippocampus. These findings suggested a potential association between maintaining oral health and reduced risk of AD and cognitive impairment. This study addresses a critical gap in understanding how OP may associate with the development of AD.\n                  <\/jats:p>","DOI":"10.1177\/00220345251412305","type":"journal-article","created":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T04:41:34Z","timestamp":1770871294000},"page":"1266-1276","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Oral Pain and Alzheimer\u2019s Disease: Prospective Cohort and Cross-Sectional Analyses"],"prefix":"10.1177","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6141-1864","authenticated-orcid":false,"given":"W.","family":"Li","sequence":"first","affiliation":[{"name":"State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.","family":"Hu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Stomatology, China Medical University, Shenyang, Liaoning, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Liao","sequence":"additional","affiliation":[{"name":"West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Lin","sequence":"additional","affiliation":[{"name":"School of Stomatology, China Medical University, Shenyang, Liaoning, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Oral Surgery, Shanghai Ninth People\u2019s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Lan","sequence":"additional","affiliation":[{"name":"Applied Oral Sciences and Community Dental Care, Faculty of Dentistry, The University of Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2008-4816","authenticated-orcid":false,"given":"H.","family":"Zhao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5665-0139","authenticated-orcid":false,"given":"H.","family":"Xu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Research Unit of Oral Carcinogenesis and Management, Chinese Academy of Medical Sciences, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,2,11]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"crossref","unstructured":"Amieva H Meillon C Proust-Lima C Dartigues JF. 2019. Is low psychomotor speed a marker of brain vulnerability in late life? Digit symbol substitution test in the prediction of Alzheimer Parkinson stroke disability and depression. Dement Geriatr Cogn Disord. 47(4\u20136):297\u2013305. https:\/\/doi.org\/10.1159\/000500597","DOI":"10.1159\/000500597"},{"key":"e_1_3_2_3_1","doi-asserted-by":"crossref","unstructured":"Avellan NL et al. 2005. Painful tooth stimulation elevates matrix metalloproteinase-8 levels locally in human gingival crevicular fluid. J Dent Res. 84(4):335\u2013339. https:\/\/doi.org\/10.1177\/154405910508400408","DOI":"10.1177\/154405910508400408"},{"key":"e_1_3_2_4_1","doi-asserted-by":"crossref","unstructured":"Casanova R et al. 2024. Associations of plasma proteomics and age-related outcomes with brain age in a diverse cohort. Geroscience. 46(4):3861\u20133873. https:\/\/doi.org\/10.1007\/s11357-024-01112-4","DOI":"10.1007\/s11357-024-01112-4"},{"key":"e_1_3_2_5_1","doi-asserted-by":"crossref","unstructured":"Cetinsoy O et al. 2024. Gene association study of the urokinase plasminogen activator and its receptor gene in Alzheimer\u2019s disease. J Alzheimers Dis. 99(1):241\u2013250. https:\/\/doi.org\/10.3233\/jad-231383","DOI":"10.3233\/JAD-231383"},{"key":"e_1_3_2_6_1","doi-asserted-by":"crossref","unstructured":"Chung JW et al. 2004. Chronic orofacial pain among korean elders: prevalence and impact using the graded chronic pain scale. Pain. 112(1\u20132):164\u2013170. https:\/\/doi.org\/10.1016\/j.pain.2004.08.014","DOI":"10.1016\/j.pain.2004.08.014"},{"key":"e_1_3_2_7_1","doi-asserted-by":"crossref","unstructured":"Collu R Giunti E Daley S Chen M Xia W. 2023. Angiotensin-converting enzyme inhibitors and statins therapies-induced changes in omics profiles in humans and transgenic tau mice. Biomed Pharmacother. 168:115756. https:\/\/doi.org\/10.1016\/j.biopha.2023.115756","DOI":"10.1016\/j.biopha.2023.115756"},{"key":"e_1_3_2_8_1","doi-asserted-by":"crossref","unstructured":"Conte M et al. 2021. Disease-specific plasma levels of mitokines FGF21 GDF15 and humanin in type II diabetes and Alzheimer\u2019s disease in comparison with healthy aging. Geroscience. 43(2):985\u20131001. https:\/\/doi.org\/10.1007\/s11357-020-00287-w","DOI":"10.1007\/s11357-020-00287-w"},{"key":"e_1_3_2_9_1","doi-asserted-by":"crossref","unstructured":"Cui S-S Jiang Q-W Chen S-D. 2023. Sex difference in biological change and mechanism of Alzheimer\u2019s disease: from macro- to micro-landscape. Ageing Res Rev. 87:101918. https:\/\/doi.org\/10.1016\/j.arr.2023.101918","DOI":"10.1016\/j.arr.2023.101918"},{"key":"e_1_3_2_10_1","doi-asserted-by":"crossref","unstructured":"Daly B et al. 2017. Evidence summary: the relationship between oral health and dementia. Br Dent J. 223(11):846\u2013853. https:\/\/doi.org\/10.1038\/sj.bdj.2017.992","DOI":"10.1038\/sj.bdj.2017.992"},{"key":"e_1_3_2_11_1","doi-asserted-by":"crossref","unstructured":"Delwel S et al. 2019. Orofacial pain and its potential oral causes in older people with mild cognitive impairment or dementia. J Oral Rehabil. 46(1):23\u201332. https:\/\/doi.org\/10.1111\/joor.12724","DOI":"10.1111\/joor.12724"},{"key":"e_1_3_2_12_1","doi-asserted-by":"crossref","unstructured":"Dibello V et al. 2021. Oral frailty and neurodegeneration in Alzheimer\u2019s disease. Neural Regen Res. 16(11):2149\u20132153. https:\/\/doi.org\/10.4103\/1673-5374.310672","DOI":"10.4103\/1673-5374.310672"},{"key":"e_1_3_2_13_1","doi-asserted-by":"crossref","unstructured":"Dibello V et al. 2023. Oral frailty indicators to target major adverse health-related outcomes in older age: a systematic review. Geroscience. 45(2):663\u2013706. https:\/\/doi.org\/10.1007\/s11357-022-00663-8","DOI":"10.1007\/s11357-022-00663-8"},{"key":"e_1_3_2_14_1","doi-asserted-by":"crossref","unstructured":"Dong H. 2023. Multisite chronic pain: a risk factor for dementia. Nat Rev Neurol. 19(6):331\u2013332. https:\/\/doi.org\/10.1038\/s41582-023-00807-0","DOI":"10.1038\/s41582-023-00807-0"},{"key":"e_1_3_2_15_1","doi-asserted-by":"crossref","unstructured":"Elovainio M et al. 2023. Association of social isolation and loneliness with risk of incident hospital-treated infections: an analysis of data from the UK Biobank and Finnish Health and Social Support studies. Lancet Public Health. 8(2):e109\u2013e118. https:\/\/doi.org\/10.1016\/s2468-2667(22)00253-5","DOI":"10.1016\/S2468-2667(22)00253-5"},{"key":"e_1_3_2_16_1","doi-asserted-by":"crossref","unstructured":"Gregson J et al. 2019. Nonproportional hazards for time-to-event outcomes in clinical trials: JACC review topic of the week. J Am Coll Cardiol. 74(16):2102\u20132112. https:\/\/doi.org\/10.1016\/j.jacc.2019.08.1034","DOI":"10.1016\/j.jacc.2019.08.1034"},{"key":"e_1_3_2_17_1","doi-asserted-by":"crossref","unstructured":"Guerreiro SR et al. 2022. Chronic pain causes tau-mediated hippocampal pathology and memory deficits. Mol Psychiatry. 27(11):4385\u20134393. https:\/\/doi.org\/10.1038\/s41380-022-01707-3","DOI":"10.1038\/s41380-022-01707-3"},{"key":"e_1_3_2_18_1","doi-asserted-by":"crossref","unstructured":"Guo Y et al. 2024. Plasma proteomic profiles predict future dementia in healthy adults. Nat Aging. 4(2):247\u2013260. https:\/\/doi.org\/10.1038\/s43587-023-00565-0","DOI":"10.1038\/s43587-023-00565-0"},{"key":"e_1_3_2_19_1","doi-asserted-by":"crossref","unstructured":"Hajishengallis G. 2022. Interconnection of periodontal disease and comorbidities: evidence mechanisms and implications. Periodontol 2000. 89(1):9\u201318. https:\/\/doi.org\/10.1111\/prd.12430","DOI":"10.1111\/prd.12430"},{"key":"e_1_3_2_20_1","doi-asserted-by":"crossref","unstructured":"Hajishengallis G Chavakis T. 2021. Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities. Nat Rev Immunol. 21(7):426\u2013440. https:\/\/doi.org\/10.1038\/s41577-020-00488-6","DOI":"10.1038\/s41577-020-00488-6"},{"key":"e_1_3_2_21_1","doi-asserted-by":"crossref","unstructured":"He L et al. 2022. Prospective associations of plasma growth differentiation factor 15 with physical performance and cognitive functions in older adults. J Gerontol A Biol Sci Med Sci. 77(12):2420\u20132428. https:\/\/doi.org\/10.1093\/gerona\/glac020","DOI":"10.1093\/gerona\/glac020"},{"key":"e_1_3_2_22_1","doi-asserted-by":"crossref","unstructured":"Higgins DM Martin AM Baker DG Vasterling JJ Risbrough V. 2018. The relationship between chronic pain and neurocognitive function: a systematic review. Clin J Pain. 34(3):262\u2013275. https:\/\/doi.org\/10.1097\/ajp.0000000000000536","DOI":"10.1097\/AJP.0000000000000536"},{"key":"e_1_3_2_23_1","doi-asserted-by":"crossref","unstructured":"Jungbauer G St\u00e4hli A Zhu X Auber Alberi L Sculean A Eick S. 2022. Periodontal microorganisms and Alzheimer disease\u2014a causative relationship? Periodontol 2000. 89(1):59\u201382. https:\/\/doi.org\/10.1111\/prd.12429","DOI":"10.1111\/prd.12429"},{"key":"e_1_3_2_24_1","doi-asserted-by":"crossref","unstructured":"Korczyn AD Grinberg LT. 2024. Is Alzheimer disease a disease? Nat Rev Neurol. 20(4):245\u2013251. https:\/\/doi.org\/10.1038\/s41582-024-00940-4","DOI":"10.1038\/s41582-024-00940-4"},{"key":"e_1_3_2_25_1","doi-asserted-by":"crossref","unstructured":"Larvin H et al. 2023. The impact of study factors in the association of periodontal disease and cognitive disorders: systematic review and meta-analysis. Age Ageing. 52(2):afad015. https:\/\/doi.org\/10.1093\/ageing\/afad015","DOI":"10.1093\/ageing\/afad015"},{"key":"e_1_3_2_26_1","doi-asserted-by":"crossref","unstructured":"Lin C-S et al. 2024. An umbrella review on the association between factors of oral health and cognitive dysfunction. Ageing Res Rev. 93:102128. https:\/\/doi.org\/10.1016\/j.arr.2023.102128","DOI":"10.1016\/j.arr.2023.102128"},{"key":"e_1_3_2_27_1","doi-asserted-by":"crossref","unstructured":"Lobbezoo F Parisius KGH Verhoeff MC. 2024. Orofacial pain and dysfunction in patients with special needs with a focus on interdisciplinarity. Pain. 165(11S):S15\u2013S22. https:\/\/doi.org\/10.1097\/j.pain.0000000000003302","DOI":"10.1097\/j.pain.0000000000003302"},{"key":"e_1_3_2_28_1","doi-asserted-by":"crossref","unstructured":"MacAuley Y O\u2019Donnell P Duncan HF. 2013. Dental pain. BMJ. 347:f6539. https:\/\/doi.org\/10.1136\/bmj.f6539","DOI":"10.1136\/bmj.f6539"},{"key":"e_1_3_2_29_1","doi-asserted-by":"crossref","unstructured":"Macedo AC et al. 2024. Prevalence of orofacial pain in individuals with mild cognitive impairment or dementia: a systematic review and meta-analysis. Gerodontology. 41(3):335\u2013345. https:\/\/doi.org\/10.1111\/ger.12740","DOI":"10.1111\/ger.12740"},{"key":"e_1_3_2_30_1","doi-asserted-by":"crossref","unstructured":"Millet A Ledo JH Tavazoie SF. 2024. An exhausted-like microglial population accumulates in aged and APOE4 genotype Alzheimer\u2019s brains. Immunity. 57(1):153\u2013170.e6. https:\/\/doi.org\/10.1016\/j.immuni.2023.12.001","DOI":"10.1016\/j.immuni.2023.12.001"},{"key":"e_1_3_2_31_1","doi-asserted-by":"crossref","unstructured":"Sadlon A et al. 2024. Association of chronic pain with biomarkers of neurodegeneration microglial activation and inflammation in cerebrospinal fluid and impaired cognitive function. Ann Neurol. 95(1):195\u2013206. https:\/\/doi.org\/10.1002\/ana.26804","DOI":"10.1002\/ana.26804"},{"key":"e_1_3_2_32_1","doi-asserted-by":"crossref","unstructured":"Shungin D et al. 2019. Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. Nat Commun. 10(1):2773. https:\/\/doi.org\/10.1038\/s41467-019-10630-1","DOI":"10.1038\/s41467-019-10630-1"},{"key":"e_1_3_2_33_1","doi-asserted-by":"crossref","unstructured":"Sun N et al. 2023. Human microglial state dynamics in Alzheimer\u2019s disease progression. Cell. 186(20):4386\u20134403.e29. https:\/\/doi.org\/10.1016\/j.cell.2023.08.037","DOI":"10.1016\/j.cell.2023.08.037"},{"key":"e_1_3_2_34_1","doi-asserted-by":"crossref","unstructured":"Suthana NA et al. 2015. High-resolution 7T fMRI of human hippocampal subfields during associative learning. J Cogn Neurosci. 27(6):1194\u20131206. https:\/\/doi.org\/10.1162\/jocn_a_00772","DOI":"10.1162\/jocn_a_00772"},{"key":"e_1_3_2_35_1","doi-asserted-by":"crossref","unstructured":"Tansley S et al. 2022. Microglia-mediated degradation of perineuronal nets promotes pain. Science. 377(6601):80\u201386. https:\/\/doi.org\/10.1126\/science.abl6773","DOI":"10.1126\/science.abl6773"},{"key":"e_1_3_2_36_1","doi-asserted-by":"crossref","unstructured":"van de Rijt LJ Feast AR Vickerstaff V Lobbezoo F Sampson EL. 2020. Prevalence and associations of orofacial pain and oral health factors in nursing home residents with and without dementia. Age Ageing. 49(3):418\u2013424. https:\/\/doi.org\/10.1093\/ageing\/afz169","DOI":"10.1093\/ageing\/afz169"},{"key":"e_1_3_2_37_1","doi-asserted-by":"crossref","unstructured":"Walker RM et al. 2024. The circulating proteome and brain health: Mendelian randomisation and cross-sectional analyses. Transl Psychiatry. 14(1):204. https:\/\/doi.org\/10.1038\/s41398-024-02915-x","DOI":"10.1038\/s41398-024-02915-x"},{"key":"e_1_3_2_38_1","doi-asserted-by":"crossref","unstructured":"Wang D et al. 2024. Association between periodontal diseases and chronic obstructive pulmonary disease: evidence from sequential cross-sectional and prospective cohort studies based on uk biobank. J Clin Periodontol. 51(1):97\u2013107. https:\/\/doi.org\/10.1111\/jcpe.13890","DOI":"10.1111\/jcpe.13890"},{"key":"e_1_3_2_39_1","doi-asserted-by":"crossref","unstructured":"Wu B et al. 2023. Diabetes edentulism and cognitive decline: a 12-year prospective analysis. J Dent Res. 102(8):879\u2013886. https:\/\/doi.org\/10.1177\/00220345231155825","DOI":"10.1177\/00220345231155825"},{"key":"e_1_3_2_40_1","doi-asserted-by":"crossref","unstructured":"Yassa MA et al. 2010. High-resolution structural and functional MRI of hippocampal CA3 and dentate gyrus in patients with amnestic mild cognitive impairment. Neuroimage. 51(3):1242\u20131252. https:\/\/doi.org\/10.1016\/j.neuroimage.2010.03.040","DOI":"10.1016\/j.neuroimage.2010.03.040"},{"key":"e_1_3_2_41_1","doi-asserted-by":"crossref","unstructured":"Yoshiji S et al. 2023. Proteome-wide Mendelian randomization implicates nephronectin as an actionable mediator of the effect of obesity on COVID-19 severity. Nat Metabol. 5(2):248\u2013264. https:\/\/doi.org\/10.1038\/s42255-023-00742-w","DOI":"10.1038\/s42255-023-00742-w"},{"key":"e_1_3_2_42_1","doi-asserted-by":"crossref","unstructured":"Zhang Y et al. 2023. Identifying modifiable factors and their joint effect on dementia risk in the UK Biobank. Nat Hum Behav. 7(7):1185\u20131195. https:\/\/doi.org\/10.1038\/s41562-023-01585-x","DOI":"10.1038\/s41562-023-01585-x"},{"key":"e_1_3_2_43_1","doi-asserted-by":"crossref","unstructured":"Zhang Y-B et al. 2021. Associations of healthy lifestyle and socioeconomic status with mortality and incident cardiovascular disease: two prospective cohort studies. BMJ. 373:n604. https:\/\/doi.org\/10.1136\/bmj.n604","DOI":"10.1136\/bmj.n604"},{"key":"e_1_3_2_44_1","doi-asserted-by":"crossref","unstructured":"Zhao W Zhao L Chang X Lu X Tu Y. 2023. Elevated dementia risk cognitive decline and hippocampal atrophy in multisite chronic pain. Proc Natl Acad Sci U S A. 120(9):e2215192120. https:\/\/doi.org\/10.1073\/pnas.2215192120","DOI":"10.1073\/pnas.2215192120"}],"container-title":["Journal of Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00220345251412305","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00220345251412305","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00220345251412305","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T09:22:36Z","timestamp":1793092956000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00220345251412305"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,11]]},"references-count":43,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["10.1177\/00220345251412305"],"URL":"https:\/\/doi.org\/10.1177\/00220345251412305","relation":{},"ISSN":["0022-0345","1544-0591"],"issn-type":[{"value":"0022-0345","type":"print"},{"value":"1544-0591","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,11]]}}}