{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T12:17:40Z","timestamp":1783253860428,"version":"3.54.6"},"reference-count":33,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"the Beijing Natural Science Foundation","award":["7242173, L242157"],"award-info":[{"award-number":["7242173, L242157"]}]},{"name":"the Clinical Medicine Plus X-Young Scholars Project of Peking University, the Fundamental Research Funds for the Central Universities","award":["PKU2025PKULCXQ040"],"award-info":[{"award-number":["PKU2025PKULCXQ040"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Dent Res"],"abstract":"<jats:p>\n                    Polyetheretherketone (PEEK) is a promising implant material due to its excellent physicochemical properties and bonelike mechanical strength. However, its inherent lack of antibacterial and osteogenic activities limits broader clinical application. In this study, gold nanoparticles of three sizes were synthesized and immobilized onto the PEEK surface via polydopamine-assisted deposition, constructing a functional coating. The results demonstrated that the coated PEEK exhibited significantly enhanced antibacterial performance, which was more pronounced with smaller nanoparticle sizes. Moreover, the modified surface favored the early adhesion of bone mesenchymal stem cells. Both\n                    <jats:italic toggle=\"yes\">in vitro<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">in vivo<\/jats:italic>\n                    experiments confirmed that this coating effectively promoted the osseointegration of PEEK implants. In summary, this work presents a potential surface treatment strategy to endow PEEK with enhanced osteogenic and antimicrobial properties.\n                  <\/jats:p>","DOI":"10.1177\/00220345261454554","type":"journal-article","created":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T10:44:57Z","timestamp":1783075497000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Gold Nanoparticles Enhance the Antibacterial and Osteogenic Properties of Polyetheretherketone"],"prefix":"10.1177","author":[{"given":"H.","family":"Tang","sequence":"first","affiliation":[{"name":"Department of Dental Materials, Peking University School and Hospital of Stomatology &amp; National Center for Stomatology &amp; National Clinical Research Center for Oral Diseases &amp; National Engineering Research Center of Oral Biomaterials and Digital Medical Devices &amp; Beijing Key Laboratory of Digital Stomatology &amp; NHC Key Laboratory of Digital Stomatology &amp; NMPA Key Laboratory for Dental Materials, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Yan","sequence":"additional","affiliation":[{"name":"Simpson Querrey Institute for BioNanotechnology, Chicago, IL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.","family":"Zhan","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Capital Medical University, Beijing Anzhen Hospital, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Dental Materials, Peking University School and Hospital of Stomatology &amp; National Center for Stomatology &amp; National Clinical Research Center for Oral Diseases &amp; National Engineering Research Center of Oral Biomaterials and Digital Medical Devices &amp; Beijing Key Laboratory of Digital Stomatology &amp; NHC Key Laboratory of Digital Stomatology &amp; NMPA Key Laboratory for Dental Materials, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bai","sequence":"additional","affiliation":[{"name":"Department of Dental Materials, Peking University School and Hospital of Stomatology &amp; National Center for Stomatology &amp; National Clinical Research Center for Oral Diseases &amp; National Engineering Research Center of Oral Biomaterials and Digital Medical Devices &amp; Beijing Key Laboratory of Digital Stomatology &amp; NHC Key Laboratory of Digital Stomatology &amp; NMPA Key Laboratory for Dental Materials, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Dental Materials, Peking University School and Hospital of Stomatology &amp; National Center for Stomatology &amp; National Clinical Research Center for Oral Diseases &amp; National Engineering Research Center of Oral Biomaterials and Digital Medical Devices &amp; Beijing Key Laboratory of Digital Stomatology &amp; NHC Key Laboratory of Digital Stomatology &amp; NMPA Key Laboratory for Dental Materials, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5712-1423","authenticated-orcid":false,"given":"D.","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Dental Materials, Peking University School and Hospital of Stomatology &amp; National Center for Stomatology &amp; National Clinical Research Center for Oral Diseases &amp; National Engineering Research Center of Oral Biomaterials and Digital Medical Devices &amp; Beijing Key Laboratory of Digital Stomatology &amp; NHC Key Laboratory of Digital Stomatology &amp; NMPA Key Laboratory for Dental Materials, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,3]]},"reference":[{"issue":"3","key":"e_1_3_2_2_1","first-page":"1022","article-title":"Osseointegration of implants\u2014a biological and clinical overview","volume":"2","author":"Albrektsson T","year":"2017","unstructured":"Albrektsson T, Chrcanovic B, Jacobsson M, Wennerberg A. 2017. 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