{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T12:12:24Z","timestamp":1777810344707,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[1984,10,1]],"date-time":"1984-10-01T00:00:00Z","timestamp":465436800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[1984,10]]},"abstract":"<jats:p>Subsurface enamel lesions and root surface caries-like lesions were consistently produced in vitro using Streptococcus mutans FA1 cultured in thioglycollate broth containing 3.5% w\/v dextrose and 2% w\/v gelatin. When viewed in polarized light and after imbibition in water, the enamel lesions had a negatively birefringent surface zone and positively birefringent body of the lesion. Those lesions produced after six weeks, after imbibition in quinoline, exhibited a dark zone. The root surface caries-like lesions exhibited a lessradiolucent surface zone above a heavily demineralized body of the lesion. However, no reactionary dentin was seen in the in vitro lesions.<\/jats:p>","DOI":"10.1177\/00220345840630100201","type":"journal-article","created":{"date-parts":[[2010,11,28]],"date-time":"2010-11-28T21:14:56Z","timestamp":1290978896000},"page":"1186-1189","source":"Crossref","is-referenced-by-count":39,"title":["A Model for Producing Caries-like Lesions in Enamel and Dentin Using Oral Bacteria in vitro"],"prefix":"10.1177","volume":"63","author":[{"given":"B.H.","family":"Clarkson","sequence":"first","affiliation":[{"name":"Dows Institute for Dental Research, College of Dentistry, The University of Iowa, Iowa City, Iowa 52242"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.S.","family":"Wefel","sequence":"additional","affiliation":[{"name":"Dows Institute for Dental Research, College of Dentistry, The University of Iowa, Iowa City, Iowa 52242"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Miller","sequence":"additional","affiliation":[{"name":"Dows Institute for Dental Research, College of Dentistry, The University of Iowa, Iowa City, Iowa 52242"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1984,10,1]]},"reference":[{"key":"atypb1","unstructured":"Berkowitz, B.K.B.; Holland, G.R.; and Moxham, B.J. 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