{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T21:50:54Z","timestamp":1791841854839,"version":"4.3.4"},"reference-count":30,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[1988,10,1]],"date-time":"1988-10-01T00:00:00Z","timestamp":591667200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[1988,10]]},"abstract":"<jats:p>Three groups of weanling, Sprague-Dawley-derived rats were inoculated with Actinomyces viscosus M-100 and fed powdered diet containing either 67%, 5%, or 0% confectioner's sugar. Two further groups were fed diet containing 5% confectioner's sugar and inoculated with Streptococcus sobrinus 6715 or S. sobrinus 6715 plus A. viscosus M-100. The most coronal 1 mm of gingiva was removed from maxillary and mandibular right molar quadrants (gingivectomy), and the animals re-inoculated following gingivectomy. The animals were killed 64 days following gingivectomy, and the lingual surface of mandibular first molar roots was measured for exposed root-surface area and root caries. In the groups of rats infected with A. viscosus M-100, root caries area was significantly greater in the group fed diet containing 67% confectioner's sugar. Sucrose level did not significantly affect the amount of exposed lingual first molar root area regardless of whether the tooth had been subjected to a gingivectomy. In the groups of rats receiving diet containing 5% confectioner's sugar, there were no significant differences in root caries area or exposed root-surface area, regardless of the infection status of the animals. In the rat model presented here, a high level of dietary sucrose was a necessary condition for the initiation of root caries in the absence of other readily fermentable carbohydrates.<\/jats:p>","DOI":"10.1177\/00220345880670101901","type":"journal-article","created":{"date-parts":[[2010,11,28]],"date-time":"2010-11-28T21:14:56Z","timestamp":1290978896000},"page":"1342-1345","source":"Crossref","is-referenced-by-count":5,"title":["The Effects of Different Levels of Dietary Sucrose on Root Caries subsequent to Gingivectomy in Conventional Rats Infected with Actinomyces viscosus M-100"],"prefix":"10.1177","volume":"67","author":[{"given":"A.R.","family":"Firestone","sequence":"first","affiliation":[{"name":"Department of Restorative Dentistry, School of Dentistry, University of Alabama at Birmingham, University Station, Birmingham, Alabama 35294"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.N.","family":"Graves","sequence":"additional","affiliation":[{"name":"Department of Physiology and Biophysics, University of Alabama at Birmingham, University Station, Birmingham, Alabama 35294"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.F.","family":"Feagin","sequence":"additional","affiliation":[{"name":"Department of Physiology and Biophysics, University of Alabama at Birmingham, University Station, Birmingham, Alabama 35294"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1988,10,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1159\/000261002"},{"key":"atypb2","first-page":"295","volume":"62","author":"DePalma, J.","year":"1983","journal-title":"J Dent Res"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1177\/00220345880670010801"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1177\/00220345870660101401"},{"key":"atypb5","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1159\/000261102","volume":"22","author":"Firestone, A.R.","year":"1988","journal-title":"Caries Res"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1159\/000261102"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(72)90157-4"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(66)90220-2"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(73)90109-X"},{"key":"atypb10","unstructured":"Guggenheim, B.; Lutz, F.; and Schupbach, P. (1987): Experimental Root Surface and Dentinal Caries in Rats. In: Dentine and Dentine Reactions in the Oral Cavity , A. Thylstrup, S.A. Leach and V. Qvist, Eds. 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(1977): Animal Models in Dental Research, Birmingham, Alabama: The University of Alabama Press , pp. 266-267."},{"key":"atypb21","doi-asserted-by":"crossref","unstructured":"Navia, J.M. (1984): The Value of Animal Models to Predict the Caries-promoting Properties of Human Diet or Dietary Components. In: Cariology Today, B. Guggenheim, Ed. Basel: Karger, pp. 154-165.","DOI":"10.1159\/000408734"},{"key":"atypb22","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/97.1.133"},{"key":"atypb23","unstructured":"Orcutt, R.P. (1981): The Care and Quality of Animals Prior to Experimentation . In: Symposium on Animal Models In Cariology, J.M. Tanzer, Ed. Sp. Supp. Microbiology Abstracts, Washington, D.C.: Information Retrieval, Inc., pp. 67-75."},{"key":"atypb24","unstructured":"Rosen, S. (1984): Alveolar Bone Loss and Root Caries In Rice Rats On Diets Containing Various Concentrations of Sucrose. In: Foods, Nutrition and Dental Health, Vol. 4, J.J. Hefferren, W.A. Ayer, H.M. Koehler, and C.T. 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